Answered: b) Show a complete reaction mechanism…

b) Show a complete reaction mechanism for the synthesis of compound K via malonic ester synthesis. Show all the reagents and draw the intermediate structures. ÇOOH Compound K

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter19: Aldehydes And Ketones: Nucleophilic Addition Reactions

Section19.SE: Something Extra

Problem 28VC

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Concept explainers

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.

Question

b) Show a complete reaction mechanism for the synthesis of compound K via
malonic ester synthesis. Show all the reagents and draw the intermediate
structures.
COOH
Compound K

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