(i) Explain the role of Ras.GTP and Rac.GTP in the formation of active AP-1 during T- cell activation. (ii) Cadmium ions have been shown to be selective blockers of membrane calcium channels. Suppose T lymphocytes are cultured in the presence of cadmium chloride, explain what happens to TCR-triggered signal transduction.
(i) Explain the role of Ras.GTP and Rac.GTP in the formation of active AP-1 during T- cell activation. (ii) Cadmium ions have been shown to be selective blockers of membrane calcium channels. Suppose T lymphocytes are cultured in the presence of cadmium chloride, explain what happens to TCR-triggered signal transduction.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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![(i)
Explain the role of Ras.GTP and Rac.GTP in the formation of active AP-1 during T-
cell activation.
(ii)
Cadmium ions have been shown to be selective blockers of membrane calcium
channels. Suppose T lymphocytes are cultured in the presence of cadmium chloride,
explain what happens to TCR-triggered signal transduction.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F2bd7ab3d-b8dc-41ee-858a-0074392e61c1%2Fce087663-ad34-4ca4-841e-6be596c318f5%2Fs1k6epl_processed.png&w=3840&q=75)
Transcribed Image Text:(i)
Explain the role of Ras.GTP and Rac.GTP in the formation of active AP-1 during T-
cell activation.
(ii)
Cadmium ions have been shown to be selective blockers of membrane calcium
channels. Suppose T lymphocytes are cultured in the presence of cadmium chloride,
explain what happens to TCR-triggered signal transduction.
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