Derivatives of purines and pyrimidines make up the base component of nucleotides. Н HCG 6 N 5 7 Select the positions in the purine ring of a purine nucleotide in DNA that have the potential to form hydrogen bonds but do not participate in Watson-Crick base pairing. HC 3 N-9 C-2 8 CH C-4 9 N-7 N C-6 H Purine C-8 C-5 N-3 N-1
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- HN N C N H₂N HN پرسپولیو D B CH₂ -N N NH₂ E When part of a nucleotide in a nucleic acid chain, which of the following may base pair with thymine nucleotides? Choose all correct answers and assume normal Watson-Crick base pairing.Given a primer sequence 3’- CTGGGAAACATTCTGGAT - 5’, compute for the melting temperature of this 18-mer.Derivatives of purines and pyrimidines make up the base component of nucleotides. Select the positions in the purine ring of a purine nucleotide in DNA that have the potential to form H. hydrogen bonds but do not participate in Watson–Crick 6 base pairing. N С-6 N-1 8 CH C-5 12 HC 4 9 С-2 N. H С-8 Purine N-7 N-9 N-3 O C-4 O O
- The specificity of Watson-Crick nucleobase pairing enables the biological information to be encoded and passed down through generations of cells and organisms. This specificity arises from the chemical structure of the base pairs, namely the pattern of hydrogen bond donors and acceptors that stabilize only two pairing interactions] relative to the others. How many possible pairwise interactions could potentially exist at a single position within a sequence, including the correct pairs, and all possible other combinations of DNA bases?In the Watson-Crick model for the DNA double helix (B form) the A-T and G-C base pairs share all but one of the following properties. Which is the exception? None of the proton-binding groups in the purine and pyrimidine bases is in its charged or ionized form. The plane of the base pair is roughly perpendicular to the axis of the helix in each case. The number of hydrogen bonds formed between the two bases of the base pair is the same. O The distance between the two glycosidic (base-sugar) bonds is the same in both base pairs, within a few tenths of an angstrom.Draw the structure of the following DNA sequence (5’-AG-3’) hydrogen bonded through Watson-Crick base pairing to the complementary PNA sequence (Cterminus-TC-Nterminus). Make sure to include both the sugar phosphate backbone of your DNA sequence, as well as the peptide backbone of your PNA sequence. DNA: 5’-AG-3’ PNA: (C)-TC-(N)
- Choose all of the statements that correctly describe the base pairs drawn below. A C H H-N -H-N N-H- -N B H D موعة Rita N -H---- 2 NHN O- -H-N H -H- N- -H-N The non-Watson-Crick base pair shown in A is much less stable than the base pairs shown in B and C, because the smaller size of the two pyrimidine bases induces a distortion in the structure of the double helix that decreases the stability of the helix when compared to helices with the normal Watson-Crick base pairs. The base pair shown in B is found in BOTH DNA and RNA The base pair shown in C is found ONLY in RNA and NOT DNA The base pair seen in B is more stable than the Watson-Crick base pair shown in C partly because of a larger number of hydrogen bonds and partly because of more favourable pi-stacking interactions with adjacent base pairs.The specificity of Watson-Crick nucleobase pairing enables the biological information to be encoded and passed down through generations of cells and organisms. This specificity arises from the chemical structure of the base pairs, namely the pattern of hydrogen bond donors and acceptors that stabilize only two pairing interaction relative to the others. How many possible pairwise interactions could potentially exist at a single position within a sequence, including the correct pairs, and all possible other combinations of DNA bases?团 X .. Structure and Nomenclature How many molecules of water were formed from the complex of the giver structure? Give ONLY the NUMBER of water molecules. Name the first nucleotide from the 3' to 5' end. Use the correct/appropriate punctuations, spacing and letter case based on the nomenclature. NH, N. to OP-0 OP- -0 O OH NH: NH; -0- NH NH, OP-O- OH OH 0P- 0 0=P-0- OH OH 1:52 pm O Type here to search 4) ENG 昆 11/10/2021
- Given the sequence shown below, write the complementary DNA sequence, using the base-pairing rules, as well as the directionality of the strands: 5'- CGAGGCTAGGTTAACCTG-3'Draw the structure of the standard Watson-Crick base-p airs involving the nucleotides dAMP,dGMP, dTMP, and dCMP. Clearly indicate the hydrogen bonds and show the structures as they wouldappear in th e double helix (Haworth projections for ribose).The formation of a double-stranded structure must obey the rule that adenine hydrogen bonds to thymine (or uracil in RNA) and cytosine hydrogen bonds to guanine. Discuss reasons why complementarity is an important feature of DNA and RNA structure and function.