Chemistry: The Molecular Science
5th Edition
ISBN:9781285199047
Author:John W. Moore, Conrad L. Stanitski
Publisher:John W. Moore, Conrad L. Stanitski
Chapter10: Fuels, Organic Chemicals, And Polymers
Section: Chapter Questions
Problem IISP
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Question
![Determine and label the configuration of each chiral carbon in the molecule shown below.
HN
B
O FI
OH
The molecule shown below is the synthetic drug Latuda (Lurasidone) that is prescribed for
antipsychotic for the treatment of schizophrenia in adults and adolescents (13-17 years).
Examine the molecule carefully and answer the following questions.
H
'N
(S)
H
INH
(R) (S)
(R)
IH
H
(S)
O
(S)
a) Identify and label the functional groups in the molecule.
b) Confirm the configuration of each stereogenic (R/S) center the molecule.
c) Label the hybridization of all the nitrogen atoms in the molecule
d) Circle of the most basic atom in the molecule and estimate the pKa of the conjugate acid of the base.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F92c8e28b-9054-4d98-88d5-7445143d6dc4%2Fe9c1c568-081d-426f-b815-77563bfd7cb4%2Fg4wn9qs_processed.jpeg&w=3840&q=75)
Transcribed Image Text:Determine and label the configuration of each chiral carbon in the molecule shown below.
HN
B
O FI
OH
The molecule shown below is the synthetic drug Latuda (Lurasidone) that is prescribed for
antipsychotic for the treatment of schizophrenia in adults and adolescents (13-17 years).
Examine the molecule carefully and answer the following questions.
H
'N
(S)
H
INH
(R) (S)
(R)
IH
H
(S)
O
(S)
a) Identify and label the functional groups in the molecule.
b) Confirm the configuration of each stereogenic (R/S) center the molecule.
c) Label the hybridization of all the nitrogen atoms in the molecule
d) Circle of the most basic atom in the molecule and estimate the pKa of the conjugate acid of the base.
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