Match each of the changes that can contribute to cancer with its correct description. Loss of function of regulators that send old or damaged cells into apoptosis Hyperactivation of signalling pathways that tell the cell to grow and divide 1. Sustaining proliferative signalling Loss of function of structural proteins that anchor cells to surrounding tissue and/or activation of cell migration 2. Evading growth suppressors 3. Activating invasion and metastasis Loss of function of 4. Enabling replicative immortality regulators that stop inappropriate growth and cell division 5. Inducing angiogenesis 6. Resisting cell death Loss of function of regulators that force aging cells to exit the cell cycle and enter GO or replicative senescence
Match each of the changes that can contribute to cancer with its correct description. Loss of function of regulators that send old or damaged cells into apoptosis Hyperactivation of signalling pathways that tell the cell to grow and divide 1. Sustaining proliferative signalling Loss of function of structural proteins that anchor cells to surrounding tissue and/or activation of cell migration 2. Evading growth suppressors 3. Activating invasion and metastasis Loss of function of 4. Enabling replicative immortality regulators that stop inappropriate growth and cell division 5. Inducing angiogenesis 6. Resisting cell death Loss of function of regulators that force aging cells to exit the cell cycle and enter GO or replicative senescence
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter12: Genes And Cancer
Section: Chapter Questions
Problem 7QP
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Question
![Match each of the changes that can contribute to cancer with its correct description.
Loss of function of
regulators that send old or
damaged cells into
apoptosis
Hyperactivation of
signalling pathways that tell
the cell to grow and divide
1. Sustaining proliferative signalling
Loss of function of
structural proteins that
anchor cells to surrounding
tissue and/or activation of
cell migration
2. Evading growth suppressors
3. Activating invasion and metastasis
Loss of function of
4. Enabling replicative immortality
regulators that stop
inappropriate growth and
cell division
5. Inducing angiogenesis
6. Resisting cell death
Loss of function of
regulators that force aging
cells to exit the cell cycle
and enter GO or replicative
senescence
00](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F1fd9878e-5d1c-44c4-8729-bd9a577e83e0%2F17625860-4a15-483c-b906-965cedfc81cb%2Fnsqxb0k_processed.jpeg&w=3840&q=75)
Transcribed Image Text:Match each of the changes that can contribute to cancer with its correct description.
Loss of function of
regulators that send old or
damaged cells into
apoptosis
Hyperactivation of
signalling pathways that tell
the cell to grow and divide
1. Sustaining proliferative signalling
Loss of function of
structural proteins that
anchor cells to surrounding
tissue and/or activation of
cell migration
2. Evading growth suppressors
3. Activating invasion and metastasis
Loss of function of
4. Enabling replicative immortality
regulators that stop
inappropriate growth and
cell division
5. Inducing angiogenesis
6. Resisting cell death
Loss of function of
regulators that force aging
cells to exit the cell cycle
and enter GO or replicative
senescence
00
![Hyperactivation of
signalling pathways that tell
the cell to grow and divide
1. Sustaining proliferative signalling
Loss of function of
structural proteins that
anchor cells to surrounding
tissue and/or activation of
cell migration
2. Evading growth suppressors
3. Activating invasion and metastasis
Loss of function of
4. Enabling replicative immortality
regulators that stop
inappropriate growth and
cell division
5. Inducing angiogenesis
Loss of function of
6. Resisting cell death
regulators that force aging
cells to exit the cell cycle
and enter GO or replicative
senescence
Activation of genes that
promote growth of new
blood vessels](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F1fd9878e-5d1c-44c4-8729-bd9a577e83e0%2F17625860-4a15-483c-b906-965cedfc81cb%2F4veikmj_processed.jpeg&w=3840&q=75)
Transcribed Image Text:Hyperactivation of
signalling pathways that tell
the cell to grow and divide
1. Sustaining proliferative signalling
Loss of function of
structural proteins that
anchor cells to surrounding
tissue and/or activation of
cell migration
2. Evading growth suppressors
3. Activating invasion and metastasis
Loss of function of
4. Enabling replicative immortality
regulators that stop
inappropriate growth and
cell division
5. Inducing angiogenesis
Loss of function of
6. Resisting cell death
regulators that force aging
cells to exit the cell cycle
and enter GO or replicative
senescence
Activation of genes that
promote growth of new
blood vessels
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