Phosphofructokinase catalyzes the conversion of ... O A) oxaloacetate to citrate B) glucose to fructose 6-phosphate C) fructose 6-phosphate to fructose 1,6-bisphosphate D) pyruvate to acetyl CoA O E) a phosphorylated 6-carbon sugar to two 3-carbon sugars
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- During the metabolism of glucose in anaerobic cells, the enzyme lactate dehydrogenase is essential to allow glycolysis to continue. This enzyme catalyzes the reduction of pyruvate to lactate. Why is this so essential? OA) It lowers the pH. B) It re-oxidizes NADH to NAD+. C) Lactate stimulates hexokinase activity. D) Pyruvate inhibits pyruvate kinase.Which of these is associated with production of ATP during glycolysis? (Select all that apply) a) Conversion of 1,3-BPG to 3PG b) Conversion of 1,3-BPG to 2,3-BPG c) Conversion of PEP to pyruvate d) Conversion of 2,3-BPG to 2PG e) Phosphorylation of glucoseWhich of the following statements is/are CORRECT? OA) Phosphoenolpyruvate carboxykinase is inhibited by ADP. B) Pyruvate carboxylase is inhibited by ADP. C) Fructose-1,6-bisphosphatase is inhibited by ADP. OD) A and B. OE) B and C. 4
- The major control enzyme in glycolysis is: a) hexokinase b) phosphofructokinase c) aldolase d) pyruvate kinase In step 4, when fructose-1,6-biphosphate is cleaved, the two molecules formed are: a) GAP and DHAP b) GAP and 3-PG c) 3-PG and 2-PG d) PEP and pyruvate NAD is used in which step? A) conversion of DHAP to GAP b) conversion of GAP to 1,3-BPG c) conversion of 1,3-BPG to 3-PG d) conversion of PEP to pyrunate The number of ATP molecules formed at the substrate level in glycolysis is: a) 1 B) 2 c) 3 d) 5 The number of ATP molecules formed indirectly via oxidative phosphorylation in glycolysis is: a) 1 B) 2 c) 3 d) 5What enzyme will be used if only the non-oxidative portion of the pentose phosphate pathway is operating to produce ribose 5-phosphate? a) 6-phosphogluconate dehydrogenase b) 6-phosphoglucono-lactonase c) glucose 6 phosphate dehydrogenase d) transketolaseWhich of the following are needed to convert fructose 6-phosphate to fructose 1,6-bisphosphate? a) Phosphofructokinase, ATP, and Mg2+ b) only phosphofructokinase c) Phosphofructokinase, ADP, and Mg2+ d) only phosphofructokinase and Mg2+
- 10) The glycerol phosphate shuttle functions in. A) Lipid catabolism C) Anaerobic glycolysis for the regeneration of NAD 8) Triglyceride synthesis D) Aerobic glycolysis to transport NAH equivalents resulting from glycolysis into mitochondria. 11) In muscles, the pyruvate is converted into lactate. Find the correct statement A) During lactate formation, NADH is reconverted into NAD B) During the product of lactate two AT are produced C) Lactate is the substrate from the downstream pathway D) Lactate acts as the substrate for the formation of amino acid 12) Which of the following regulates lipolysis in adipocytes A) Activation of fatty acid synthesis mediated by CAMP 8) Glycerol phosphorylation to prevent futile esterification of fatty acids C) Activation of triglyceride lipase as a result of hormone stimulated increases in cAMP levels D) Activation of cAMP production by Insulin 13) Glycolysis consists of three irreversible steps. Which of the following enzyme catalyzes the reaction are…complex allosteric regulation of the aspartate transcarbamoylase reaction is significant because it links? a) citric acid cycle and catecholamine biosynthesis b)glycolysis and lactic acid fermentation c) opiate with neurotransmitter d) glycolysis and fatty acid metabolism e) amino acid and nitrogenous base metabolismDetermine whether the following statements are true or false:- a) The pentose phosphate pathway of glucose conversion is a supplier of NADPH (H +) for reductive syntheses. b) An overdose of insulin causes hypoglycemia in a patient with diabetes mellitus. c) Fructose-6-phosphate is an allosteric regulator of glycolysis.
- E3 of the pyruvate dehydrogenase complex performs which main function? A) removing a proton from TPP forming a carbanion b) catalyzing the condensation of the TPP carbanion with pyruvate to form hydroxyethyl-TPP c) oxidation and transfer of the hydroxyethyl group to lipoic acid d) reoxidation of lipoic acid in order to keep the reaction going Once acetyl-CoA is formed, it usually takes one of two paths. The first is further oxidation in the citric acid cycle. The second is: a) conversion to oxaloacetate which generates glucose by gluconeogenesis b) synthesis of galactose c) activates transcription factors which signal the synthesis of peptidase enzymes d) it is used in the synthesis of fatty acids.18) During glycolysis, the molecule shown at right is the substrate of a) aldolase b) triosephosphate isomerase c) glyceraldehyde 3-phosphate dehydrogenase d) phosphoglycerate mutase 0-P-O 19) fr the molecule at right (above) proceed to 2-phosphoglycerate, which of the following would be the position of the carbon marked with a star? b) c) d) H. -P=0 -0-P=0 ОН HO. HO. HO. When we break down fats (triacylglycerol), the glycerol can be converted to pyruvate (or lactate) by entering glycolysis as shown below. HO ATP ADP NAD NADH shycolysis но Om-o 20) If one molecule of glycerol is converted to one molecule of pyruvate, what is the net synthesis of ATP? a) +3 b) +2 c) +1 0 (P e) -1 f) -2 g) -3 21) If one molecule of glycerol is converted to one molecule of lactate, what is the net synthesis of NAD:H? a) +3 b) +2 c) +1 d) 0 e) -1 f) -2 g) -3 22) Consider the reaction catalyzed by phosphoglycerate mutase. Which of the following would force the reaction to go more so in the glycolysis…What two 3-carbon molecules are generated by the cleavage of fructose-1,6-bisphosphate?A) glyceraldehyde-3-phosphate and 3-phosphoglycerateB) glyceraldehyde-3-phosphate and dihydroxyacetone phosphateC) pyruvate and phosphoenolpyruvateD) enolase and 2-phosphoglycerateE) glyceraldehyde-3-phosphate and pyruvate