Select the appropriate set of reagents for the below transformation: ? NMe2 A Set A B Set B C) Set C D Set D Ph Reagent Set A: Reagent Set B: CI Me₂N Ph CICI AICI 3 Ph NMe2 Na2CO3, H₂O (work-up) Reagent Set C: Reagent Set D: 요 ZnCl2 Me,NH AcOH (cat.) Ph H Me₂N Ph
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- Identify the suitable reagents for the given reaction and arrange them accordingly. 1 OH OEt 2 OEt OEt O 1) EtOH, H₂SO4; 2) EtOH, H₂SO4 O 1) EtONa followed by H₂O; 2) TsCl/py followed by EtONa O 1) EtONa followed by H₂O; 2) NaH followed by EtBr O 1) EtOH, H₂SO4; 2) NaH followed by EtBr O 1) EtOH, H₂SO4; 2) TsCy followed by EtONaWhich reagent(s) would accomplish the synthesis showWn below? NH2 NH2 но. H3CO. A) NaBH4 В) РСС C) LAH D) Na2Cr207 / H2SO4 E) NAOH www wQ4. Provide reagents for the following transformations OH ов ОН ОН
- Identify the suitable reagents for the given reaction and arrange them accordingly. OH A+&+F OEt 1 2 OEt OEt 1) EtOH, H₂SO4; 2) EtOH, H₂SO4 1) EtONa followed by H₂O; 2) TsCl/py followed by EtONa 1) EtONa followed by H₂O; 2) NaH followed by EtBr O 1) EtOH, H₂SO4; 2) NaH followed by EtBr O 1) EtOH, H₂SO4; 2) TsCmy followed by EtONaMulti-step synthesis: Provide reagents needed for the following transformations. More than ne step is rquired for each reaction.Draw a stepwise mechanism for the following transformation: Part 1: Part 2 out of 3 Draw the mechanism that leads to the minor resonance contributor. OH OH view structure :ÖH Н30 H₂O H finish structure... OH H view structure H draw structure... HO™ H₂O H3O+ 0₂ X
- provide the missing reagents as appropriateDraw the mechanism ffrom benzaldehyde to this using: i)NaBH4 ii)TsCl, py iii)NaCN iiii)H+, H2OThe structure shown below is of Pitolisant (Waxix®), is a drug to treat narcolepsy. CI Pitolisant – Waxix® Below, see the synthesis of the compound. What are the reactions used? OMs OH OH CI CI O Two Williamson ether synthesis reactions. O Aminal formation followed by an ether interchange reaction. O An SN2 reaction followed by a Williamson synthesis.
- What are the missing reagents and compounds below A NaCN Br Br. в *OH `OTMS TMS = (CH3);Si Bra NaNHa5. Provide the missing reagent indicated by "???": Br ???Step 2: A hemiacetal formation has a similar mechanism to the hydrate reaction, except 1 equivalent of alcohol is added instead of water. 1² R₂ R₁ LOR3 R₁ R₂ The hemiacetal reaction is also reversible and can also be catalyzed by either acid or base. Hemiacetals are not usually isolated, except in the formation of 5- and 6-membered rings, as often seen in carbohydrate chemistry. Identify the hemiacetal formed from the intramolecular cyclization of the molecule shown. OH H OH R3OH OH OH OH CH₂OH NaOH ?