What is one situation where Koch’s postulates are impossible to complete? In other words, what factors about a microbe or factors about a disease make it impossible for Koch's postulate to be performed with that microbe or disease?
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What is one situation where Koch’s postulates are impossible to complete? In other words, what factors about a microbe or factors about a disease make it impossible for Koch's postulate to be performed with that microbe or disease?
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- Why is it Koch's postulates cannot be used for the microbe E. Coli. What limitations does E.coli have?The following are the limitations of Koch's postulates EXCEPT: A. some pathogens cannot grow on artificial media and therefore cannot be identified as the causative agent of the disease B. some diseases involve multiple pathogens which produce similar symptoms making it difficult to pinpoint the causative agent C. some diseases are host-specific and re-inoculation may pose ethical concerns D. some microorganisms are present in the body fluids of the infected animal which make them difficult to be culturedWhich of the following is NOT true about Koch's postulates? First developed by Robert Koch, the pioneering German microbiologist In the first step, the microbe that causes a naturally occurring disease is cultured from a "wild" (non-laboratory) animal which has that disease None of the other four answers (All are true about Koch's Postulates) They represent a process for showing a causal association between a specific microbe and a disease If the same microbe from a diseased "wild" (non-laboratory) host causes the same disease in a lab animal and it can be cultured from that lab animal, this proves that the microbe is the cause of the naturally occurring disease
- Describe the lines of proof Robert Koch used to definitivelyassociate the bacterium Mycobacterium tuberculosis with thedisease tuberculosis. How would his proof have been flawedif any of the tools he developed for studying bacterialdiseases had not been available for his study of tuberculosis?What are Koch's postulates? Discuss the importance of these postulates in the identification of bacteriaNote that it is not appropriate to self-diagnose outside of a medical context and this is a completely hypothetical scenario. Imagine you have a rash on your foot. You're concerned that it's an infection and inoculate a sample onto an agar plate. You wonder, How can I figure out whether the pathogen is a bacterium vs a eukaryote? You decide to use lab supplies to get a basic understanding of the pathogen. Be specific about what tests you use and what you expect the results to be. Limit yourself to experiments we could do in our lab. What is a procedure you could do, involving making a slide of the organism?
- List the main features of Koch's postulates and then explain how it's difficult to prove them for certain diseases?Note that it is not appropriate to self-diagnose outside of a medical context and this is a completely hypothetical scenario. Imagine you have a rash on your foot. You're concerned that it's an infection and inoculate a sample onto an agar plate. You wonder, How can I figure out whether the pathogen is a bacterium vs a eukaryote? You decide to use lab supplies to get a basic understanding of the pathogen. Be specific about what tests you use and what you expect the results to be. Limit yourself to experiments we could do in our lab. What is one experiment you could do, involving culturing the organism?In a series of infection experiments, a researcher discovers that the ID50 value for the infectious bacterium Parasiticum mucoides is 2,000, and that the ID50 for another infectious bacterium, Donoteatum thisbacterium, is 150. Given these data, a person exposed to 1,000 bacteria of each type would be more likely to be infected by which bacterium? There is no way to know given the information provided Both infections are equally likely Donoteatum thisbacterium Parasiticum mucoides
- What are Koch’s postulates and what is their importance?Robert Koch developed a set of criteria (postulates) for conclusively demonstrating the aetiology (specific cause) of an infectious disease. Which of the following is not a postulate? The infectious agent must be isolated and cultured in vitro The disease is reproduced when a pure culture of the infectious agent is inoculated into a new susceptible host The infectious agent can be recovered from the experimentally-infected host The infectious agent is present in most cases of the diseaseA suspected pathogen is observed from the blood of a diseased mouse. An investigation of the other mice in the area indicates that it is not present in healthy mice. With Koch's postulates in mind, what is the next step to determine whether or not this suspected pathogen is the cause of disease in the mouse? a) Grow the suspected pathogen in a pure culture Ob) Re-isolate the suspected pathogen and show that it is the same as the original pathogen c) Inoculate a healthy mouse with the suspected pathogen O d) Determine whether the organism in the pure culture is the same one as in the original sample