Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter28: Dna Metabolism: Replication, Recombination, And Repair
Section: Chapter Questions
Problem 17P
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Oogenesis
The formation of the ovum (mature female gamete) from undifferentiated germ cells is called oogenesis. This process takes place in the ovaries (female gonads). Oogenesis consists of three stages known as the multiplication phase, growth phase, and maturation phase.
Cell Division
Cell division involves the formation of new daughter cells from the parent cells. It is a part of the cell cycle that takes place in both prokaryotic and eukaryotic organisms. Cell division is required for three main reasons:
Question
Which of the following statements regarding DNA synthesis at the ends of linear chromosomes is true?
![Vhich of the following statements regarding DNA synthesis at the ends of linear chromosomes is true?
Telomerase, an enzyme composed of both RNA and protein, functions by cleaving the 3' overhangs that are left by DNA polymerase.
Because DNA polymerase has proofreading capabilities, replication at the ends of linear chromosomes is usually error-free, and
O II. telomerase, an enzyme composed of both RNA and protein, simply ensures that any incorporated errors are corrected.
DNA synthesis at the ends of linear chromosomes is a problem also observed in prokaryotic cells.
II.
Cancer in humans is associated with a reduction in the activity of telomerase.
DIV.
Because DNA polymerase is not able to initiate strand synthesis, linear chromosomes will have a 3' overhang at their ends. This is
OV. corrected by telomerase, an enzyme composed of both RNA and protein, which extends the ends of eukaryotic chromosomes.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F5e225dbb-3abf-4c19-a103-a9ee511f3279%2F63e4a69c-0ae1-4366-b2e8-d5dc39983527%2Fh0o0vqn_processed.png&w=3840&q=75)
Transcribed Image Text:Vhich of the following statements regarding DNA synthesis at the ends of linear chromosomes is true?
Telomerase, an enzyme composed of both RNA and protein, functions by cleaving the 3' overhangs that are left by DNA polymerase.
Because DNA polymerase has proofreading capabilities, replication at the ends of linear chromosomes is usually error-free, and
O II. telomerase, an enzyme composed of both RNA and protein, simply ensures that any incorporated errors are corrected.
DNA synthesis at the ends of linear chromosomes is a problem also observed in prokaryotic cells.
II.
Cancer in humans is associated with a reduction in the activity of telomerase.
DIV.
Because DNA polymerase is not able to initiate strand synthesis, linear chromosomes will have a 3' overhang at their ends. This is
OV. corrected by telomerase, an enzyme composed of both RNA and protein, which extends the ends of eukaryotic chromosomes.
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