SEELEY'S ANATOMY+PHYSIOLOGY
12th Edition
ISBN: 9781260172195
Author: VanPutte
Publisher: RENT MCG
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Textbook Question
Chapter 17.4, Problem 17AYP
What characteristics ofa hormone receptor make itspecific for one type of hormone?
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What characteristics of a hormone receptor make itspecific for one type of hormone?
Suppose that the circulating concentration of hor-mone is 10–10 M and the Kd for binding to its receptor is 10–8M. What fraction of the receptors will have hormone bound?If a meaningful physiological response occurs when 50% ofthe receptors have bound a hormone molecule, how muchwill the concentration of hormone have to rise to elicit aresponse? The fraction of receptors (R) bound to hormone(H) to form a receptor–hormone complex (R–H) is [R–H]/([R] + [R–H]) = [R–H]/[R]TOT = [H]/([H] + Kd).
Hormone receptor molecules are the key to understanding specific-ity of hormone action on target cells. Describe and distinguish be-tween receptors located on the cell surface and those located in the nucleus of target cells. Name two hormones whose action is medi-ated through each type of receptor.
Chapter 17 Solutions
SEELEY'S ANATOMY+PHYSIOLOGY
Ch. 17.1 - How does an endocrine gland differ from an...Ch. 17.1 - Prob. 2AYPCh. 17.1 - In what ways does the nervous system differ from...Ch. 17.1 - Name and describe the four classes of chemical...Ch. 17.2 - Prob. 5AYPCh. 17.2 - Prob. 6AYPCh. 17.2 - Prob. 7AYPCh. 17.2 - What effect does a bound hormone have on the...Ch. 17.2 - What are the two chemical categories of hormones?...Ch. 17.2 - Describe how the chemical nature of a hormone...
Ch. 17.2 - Prob. 11AYPCh. 17.2 - Why do organs regulated by protein hormones have...Ch. 17.2 - Prob. 13AYPCh. 17.2 - Describe chronic, acute, and episodic patterns of...Ch. 17.3 - Describe and give examples of the three major ways...Ch. 17.3 - Prob. 16AYPCh. 17.4 - What characteristics ofa hormone receptor make...Ch. 17.4 - What is down-regulation, and what may cause it to...Ch. 17.4 - Prob. 19AYPCh. 17.4 - What are the two classes of hormone receptors? How...Ch. 17.4 - Prob. 21AYPCh. 17.4 - Prob. 22AYPCh. 17.4 - Prob. 23AYPCh. 17.4 - What two ways can a membrane-bound receptor use to...Ch. 17.4 - Explain how the hormone-receptor complex can alter...Ch. 17.4 - List four intracellular mediators affected by G...Ch. 17.4 - Prob. 27AYPCh. 17.4 - Prob. 28AYPCh. 17.4 - Prob. 29AYPCh. 17.4 - Prob. 30AYPCh. 17 - Prob. 1RACCh. 17 - Prob. 2RACCh. 17 - Which of these can regulate the secretion of a...Ch. 17 - Prob. 4RACCh. 17 - Prob. 5RACCh. 17 - Concerning the half-lifeof hormones, a....Ch. 17 - Prob. 7RACCh. 17 - Prob. 8RACCh. 17 - Prob. 9RACCh. 17 - Prob. 10RACCh. 17 - Prob. 11RACCh. 17 - Which of these can limit a cell's response to a...Ch. 17 - Prob. 13RACCh. 17 - Prob. 14RACCh. 17 - When a hormone binds to a nuclear receptor a. DNA...Ch. 17 - Prob. 16RACCh. 17 - Prob. 1CTCh. 17 - Prob. 2CTCh. 17 - Prob. 3CTCh. 17 - Prob. 4CTCh. 17 - Prob. 5CTCh. 17 - Prob. 6CTCh. 17 - Thyroid hormones are important in regulating the...Ch. 17 - Prob. 8CTCh. 17 - Prob. 9CT
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