The prefix dis- has several senses, but its basic meaning is not, not any. Thus disbelieve means to refuse to believe and discomfort means a lack of comfort. Dis- came into English from the Old French prefix des-, which in turn came from the Latin prefix dis-, which came from the adverb dis-, meaning apart, asunder. Dis- is an important prefix that occurs very frequently in English in words such as discredit, disrepair, and disrespect.