The Willowbrook Study

Expedited review procedures are appropriate only for protocols that present no greater than "minimal risk" to subjects and involve only procedures included in federally specified categories. Population considerations, such as healthy volunteers, are only relevant insofar as they affect the assessment of risk. The IRB may not conduct an expedited review for the convenience of either the IRB or a student researcher, if the protocol is otherwise not eligible.

| The study involves no more than minimal risk and meets one of the allowable categories of expedited review specified in federal regulations. Expedited review procedures are appropriate only for protocols that present no greater than "minimal risk" to subjects and involve only procedures included in federally specified categories. Population considerations, such as healthy volunteers, are only relevant insofar as they affect the assessment of risk. The IRB may not conduct an expedited review for the convenience of either the IRB or a student researcher, if the protocol is otherwise not eligible.

The issues that were involved in the violation of the ethical principles involving human subjects include racism, paternalism, informed consent, truth telling, scientism, and whistle blowing. There were other issues that were involved in this study: double standards, maleficence, and the use of deception in research among others. The issue of racism was seen clearly in this study. Four hundred black persons were infected and two hundred served as a control group. Caucasians were not enrolled in this study. This was a violation of justice because the subjects were not treated

The central ethical conflicts of the Clara’s case are several infringements committed regarding human rights in human experimentation. According to the American Psychological Association Code of Ethics [APA] (2010) experiments such as Clara would have violated several sections from standard 8: 8.01 (obtaining institutional approval), 8.02 (participants’ informed consent), 8.04 (client/patient, student, and subordinate respect to continue in research), 8.07 (deception in research), and 8.09 (humane care). Section 8.01 indicates that researchers must obtain approval prior

In todays society, the common consensus about human experimentation is that it is unethical, however, people in the past believed it was necessary to advance scientific discoveries. The Tuskegee syphilis study is a prime example of how scientists in the past disregarded the ethics of human experimentation to enhance scientific research. The study was an experiment where four- hundred to six-hundred uneducated African American men were tricked into being tested. Most of the patients were injected with the disease and left without treatment to discover its effects, while the others were safe being used as controls. This experiment lasted for Forty years and was probably the biggest example of unethical human experimentation in America. Fortunatley, the contrivertial actions taken in the experiment lead future generations to create the law of informed consent where the patient understands what will happen during their treatment. The inspiration for researching this topic was how in “The Immortal Life of Henrietta Lacks”, by Rebecca Skloot, Henrietta was used for a scientific study without her consent. In relation to Henrietta, the men in the syphilis study were not aware of what was happening to them and were experimented on without their consent. Overall, the human experimentation in the Tuskegee syphilis study was unethical in many ways.

State institutions that house individuals with intellectual and physical disabilities have been a prominent part of history in the health professions. In 1967 in the United States, there were more than a quarter of a million state institutions that housed individuals with intellectual and physical disabilities (Waldman, 2017). One state institution that was around during that time period was Willowbrook State School which was located on Staten Island in New York City and was one of the largest run state schools for people with developmental disabilities. Willowbrook at its peak was home to over 6000 residents when its capacity was for just 4000 (Kaser, 2005). Willowbrook was a state institution that is most often described for dehumanizing its patients. Willowbrook housed both children and

When thinking about the Tuskegee experiments, the theory of utilitarianism comes to mind. This theory, generally, explains that the basis of right and wrong is determined by the outcomes of an event, therefore the welfare of the trial participants is not important if it leads to an outcome that can better the general population (Macrina). You saw this type of behavior happen in the Tuskegee trials, where participants were lead to believe they were being treated for their Syphilis by the research team, when in reality the team was collecting data to look at the mortality rates of untreated Syphilis (Emanuel). Today, there are strict guidelines in research, both nationally and internationally, that were established to hopefully prevent this sort

There are a multitude of constituents that could be modified to make these unprincipled studies ethical for subjects. The Tuskegee syphilis study was an unscrupulous experiment that illustrated the significance of morality in human experimentations. A noteworthy alteration that would be made is guaranteeing that every participant in experiments are given a full assessment of the dangers that can arise from the experiment. Consent was an element that was fundamentally nonexistent in the Tuskegee syphilis experiment, resulting in the study being expressively immoral. In addition, a momentous ethical and legal issue involved in the Tuskegee study were the counterfeited information given to the subjects and the community. David Smolin, the author of the “Tuskegee Syphilis Experiment, Social Change, and the Future

The Tuskegee study is a prime example of why ethical treatment is necessary. This study took place in 1932 and dealt with African Americans who had contracted Syphilis. They were told they would get free medical exams, free meals, and burial insurance in exchange for participating in the study. The catch was that the people participating in the study who had syphilis were not treated properly. Even when penicillin became the main treatment for syphilis, the patients were not given it and were not given the option to leave the study when this happened. Ultimately, the study got shut down because it was considered unethical due to the fact that the patients were not given enough information to give real informed consent.

Tuskegee – The doctors violated this principle by not informing the study subjects of the details of the study itself. The subjects were informed they were going to be treated for “bad blood” (CDC, 2015). At the time “bad blood” could have meant syphilis or it could have meant anemia or fatigue. None of the patients received treatment to cure their illness. Additionally, none were ever informed that they were in fact part of a study to document how syphilis progresses when left untreated. These were autonomous men who had vital information withheld from them while being subjects in a research study.

Interestingly, IRBs are set up mainly to confirm that a clinical trial is ethical and that the process will not harm patients. Whether or not the clinical trial is constructed properly or not is commented upon, but may not be a major focus of the review. For this reason, many institutions also require a concurrent review by an institutional “Office of Clinical Research” and a regular meeting of supervising clinicians during the

Science, medicine, and psychology are powerful tools capable of increasing human understanding of the world, curing diseases, or assisting individuals in living more fulfilling lives. The potential for good is drastic; however, a potential for hurt exists as well. Although history is full of stories documenting the positives of research, events of scientific research hurting individuals still haunt history. These events, including the Holocaust and the Tuskegee experiments, demonstrate instances where scientific research on human beings is clearly unethical and damaging. Due to horrific events such as these, the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research published the Ethical Principles and Guidelines for the Protection of Human Subjects of Research, or Belmont Report, in 1979.

Medical experiments on human subjects carry a great deal of ethical dilemma. In the United States, there have been various experiments made on human subjects that raised the ire of many people in the society. Many of the subjects were subject to drug experimentation, risky operations and being infected with diseases just to know how the disease affects the body. One of these experiments is the Tuskegee Syphilis Experiment conducted to unknowing subjects for 40 years.

Select two complaints presented in the Grenyer & Lewis article (see Table 1) and explain the ramifications of these violations applying the APA’s Ethical Principles of Psychologists and Code of Conduct to each situation.

Throughout history there are many examples of humans conducting experiments on other humans. Over the years human experimentation has greatly advanced the knowledge of human physiology and psychology, leading to better treatments for ailments both physical and mental as well as a better overall understanding of the human constitution. Despite all of the good which human experimentation has done for the human race there have been times when experimenters have taken human experimentation past the bounds of morality. This unethical human experimentation is most often caused when the experimenters are, in some way, able to justify their experiments.