A Typical Cold? by Brent J.F. Hill
Part III—Your Explanation of Sam’s Condition
Objectives and Issues
1. What type of disease is Sam suffering from?
Cystic Fibrosis
2. What tissues and organs does this disease affect? Once you identify all the tissues and organs, briefly explain their respective dysfunction.
Exocrine Glands – glands may become blocked, produce excessive secretions
Sweat Glands – extreme decrease in salt reabsorbtion, resulting in high salt content in sweat.
Lungs – Mucus plugging, chronic bacterial infections, pronounced inflammatory response, damaged airways leading to respiratory insufficiency, progressive decline in pulmonary function.
Male reproductive tract – males with CF are sterile due to degeneration
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One of the distinguishing features of cystic fibrosis is the thick mucus that lines both the airways and the intestinal tract of affected individuals. In the respiratory tract, this thick mucus is not removed by the cilia that usually beat and push mucus up into the throat. This thick mucus builds up in the airways, and bacteria trapped in the mucus are not removed. Thus bacterial respiratory infections are extremely common.
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4. Explain the reasoning behind the appearance of his sputum.
Sam's sputum was viscid because the excessive Chloride ions inside the cells attract water, so water does not leave the cells. This water is what makes the mucus thin and slippery. Without the water the mucus is thick and sticky.
Sam's sputum was probably green due to all of the bacteria that has built up in his respiratory tract because the mucus escalator cannot move the mucus up and out..
Textbook pg 817 5. Typically, a pulmonary function test will not be given until about age 7. However, if Sam was given a pulmonary function test it will demonstrate a decreased FEV1 (forced expiratory volume in 1 second) and FVC (forced vital capacity). Based on these hypothetical pulmonary function test results, answer the following questions:
1. What can you infer about the surface area and/or diffusion distance for gas exchange in Sam’s lungs?
I would guess that the surface area has been decreased and the diffusion distance for gas
Cystic fibrosis is a continuous, genetic disease that causes persistent lung infections and limits the ability to breathe over a period of time (Cystic Fibrosis Foundation). When an individual has cystic fibrosis, they tend to have lots of various lung problems. The overall cause of their lung problems is related to basic problems with diffusion and osmosis in the large airways of the lungs. The non-working cystic fibrosis proteins do not allow salt or water to enter the air space, resulting in the mucus layer to be extremely concentrated and very sticky. When you focus on individuals without cystic fibrosis, you can see that they have a small layer of salt water in the big airways of their lungs. This layer of salt water lies underneath
Nearly 1 in every 30 Americans are a carrier of the recessive gene that leads to CF (About Cystic Fibrosis, n.d.). Although CF is a life-threatening condition, through the advancement of treatments and care, there has been a steady increase in life expectancy and improvement in the quality of life. The current mean age of survival is now 40. Although that does not seem very high, sixty years ago, a child diagnosed with CF did not survive childhood (About Cystic Fibrosis, n.d.). CF is a complex disease, where the types and severity of symptoms can differ widely from person to person. Symptoms may include fatigue, salty-tasting skin, persistent cough with phlegm, wheezing and shortness of breath, lung infections, and poor growth and weight loss (Cystic Fibrosis Symptoms, Causes & Risk Factors, 2018). Many different factors, such as the age of diagnosis, can affect an individual's health and the course of the
Identify the disease process presented by the case study as well as the normal structure and function of the organ system and/or physiological process.
I. Which of the symptoms Cari has described are due to lack of oxygen and reduced oxygen exchange at her tissues?
5. What is (are) the potential disease or disorder? Include (a) a justification for your decision, (b) the causal agent, and (c) the mode of transmission.
Also he’s oxygen diffusion rate has increased due to the more oxygen which is absorbed by the alveoli and then circulated around the body.
These thick, secretions can also be found in the lungs, creating breathing complications and a breeding ground for bacteria.
A person can present with accumulation of viscid mucus, which is followed by obstruction and stasis. Someone might have an airway obstruction or frequent bronchial infections with resistant strains of bacteria result. Recurrent cough, production of thick, tenacious sputum can also be some more symptoms. Cystic Fibrosis has many respiratory features including hemoptysis, pneumothorax, and respiratory failure if the disease is progressive. Cystic Fibrosis can be demonstrated by elevated sodium and chloride concentration in one’s sweat. An abnormal sodium of chloride concentration can and will confirm a diagnosis of Cystic Fibrosis. One example of an abnormal level would be 60 mEq/L. Most cases of Cystic Fibrosis are diagnosed early in childhood. In about one out of every five of all Cystic Fibrosis cases do not get diagnosed or detected before the age of fifteen. Those who do not get diagnosed early in their childhood present with recurrent bronchopulmonary infections, airflow obstructions, and digital
Cystic fibrosis is an inherited life- threatening disorder that damages the lungs and digestive system. This disorder can also be known as Mucoviscidosis . Long- term issues include difficulty breathing, also coughing up sputum as a result from frequent lung infections. Sinus infections, poor growth, clubbing of the finger and toes, also infertility in men are other possible symptoms of this disorder. Different individuals may have different degrees of symptoms. Cystic fibrosis is an autosomal recessive disorder. Mutations in both copies of the gene for the protein cystic fibrosis transmembrane conductance regulatory (CFTR) is the cause of this. CFTR is involved in production of sweat, digestive fluids, and mucus. Secretions,
Cystic fibrosis, also known as CF, affects over 30,000 children and adults world-wide. CF is a disease in the lungs and digestive system and is still incurable today. It is a disease that causes thick, abnormal mucus in the lungs, nasal polyps, fatigue, and can also damage organs in a person’s body. According to www.cff.org/aboutcf, over 70% of CF patients are diagnosed at two years of age. Cystic fibrosis is one of the most life-threatening diseases in the United States and is very common amongst chronic diseases. Cystic fibrosis is most commonly diagnosed in young children and sometimes adults.
infection and that could result in respiratory failure. Also males with Cystic Fibrosis could get
Evaluate the given clinical scenario and use your knowledge of the diseases covered in Lectures.
The disease is prevelant in western society; 1 in 2500 people have the disease and an estimated 1 in 25 people are carriers. Symptoms of cystic fibrosis include shortness of breath, high risk of lung infection , malnourishment and constipation. These symptoms occur due to the production of abnormally thick mucus in the digestive and respatory systems. In the lungs, their are small air pockets known as alveoli. These pockets increase lung surface area, which increases the amount of oxygen delivered to the blood stream via diffusion. In cystic fibrosis, thickened mucus blocks the alveoli, leading to a lack of oxygen in the blood stream, stiffened lung tissue and a high risk of
CF will affect the cells in the body that makes sweat, mucus and digestive fluids that will make it slippery, however if you have a cystic fibrosis will make it thick and glue like. This will block the tubes and ducts throughout the body and build mucous inside the airways which will make it hard to breath. When the mucus traps germs and leads to infections. Patients will cystic fibrosis will often get a thick buildup of mucus of the lungs and travel to other organs. According to the article About Cystic Fibrosis (n.d) “In the lungs, the mucus clogs the airways and traps bacteria leading to infections, extensive lung damage, and eventually, respiratory failure.”
As a result of Cystic Fibrosis, the body produces unusually sticky and thick mucus that has the following effects. It makes the lungs clog with significant exposure to lung infection which threatens life. It also causes obstruction of the pancreas and prevents natural enzymes in their role of