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State true /false with reason
10. Unlike cocaine and heroin, THC is not consistently reinforcing for laboratory rodents.
11. Endocannabinoids are released primarily from terminal boutons under the influence of action potentials.
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- y "w termta. 3. Increasing the temperature of the Ringer's solution bathing the frog heart will (decrease / increase / have no effect on) the heart rate of the frog. 4. Decreasing the temperature of the Ringer's solution bathing the frog heart will (decrease / increase / have no effect on) the heart rate of the frog. PhysioEx Ex. 6 – Activity 4 1. What effect would a parasympathetic agonist have on heart rate? 2. What effect would a parasympathetic antagonist have on heart rate? 3. What two effects would a sympathetic agonist have on heart rate? 4. What two effects would a sympathetic antagonist have on heart rate? 5. In this lab you applied several drugs to a frog heart. What drug might you administer if you need to increase cardiac output without affecting stroke volume*? 6. In this lab you applied several drugs to a frog heart. What drug might you administer if you need to decrease cardiac output without affecting stroke volume? 7. In this lab you applied several drugs to a frog…Please answer Ture or False. 7. Ethanol is a glutamate agonist. 8. Withdrawal from ethanol is safer than withdrawal from heroin. 9. Detoxifying from ethanol can cause seizures. 10. Unlike cocaine and heroin, THC is not consistently reinforcing for laboratory rodents. 11. Endocannabinoids are released primarily from terminal boutons under the influence of action potentials.True or False. 1. Reboxetine exerts its therapeutic effects by stimulating the reuptake of neurotransmitters. 2. Lithium Carbonate is not effective in the management of rapid cycling bipolar disorder. 3. Tegaserod is a serotonin receptor antagonist previously indicated for IBS. 4. An inhibitory neurotransmitter prevents a neuron from firing an action potential.
- 1. Jesse age 27 complaints of muscle spasm, sweating abdominal pain and diarrhea. You know that her temperature is 101, pulse is 120 and her BP is 186/92. In reviewing her medications you note but she is taking fluoxetine (Prozac) and Sertraline (Zoloft), which life threatening events may she be experiencing? a. Neuroleptic malignant syndrome b. Monamine oxidase crisis c. Serotonin syndrome d. HyperpyrexiaDescribe the typical withdrawal symptoms associated with physical dependence on opioids, include the timing of symptoms since last dose? Explain why PCP was thought to be a useful anesthetic and why this use failed to be practical for humans. Please Help!!.. ..3. Draw the chart, demonstrating the mechanisms action of epinephrine on target cells (the typical cardiomyocytes of heart ventricles).
- Neurological symptoms associated with thiamin may be due to 1. alterations in acetylcholine synthesis. 2. ingestion of enriched grain products in the diet. 3. decreased fat intake. 4. increased thiamin intake.AZ B 3 C D 3... Refer to the given diagram of different variations of GPCRs to answer the following questions: 1. Identify the specific type of GPCR as per letters A, B, C, and D. 2. What are the typical endogenous ligands and common drugs that interact with these receptors?10. Scopolamine gr 1/300 is ordered. The drug is available in 0.4 mg/mL. How much will you give? 11. Digoxin 0.25 mg PO is ordered. The medication comes in 0.5 mg tablets. How many will you give?
- 6. The doctor has ordered iiiss drams of Milk of Magnesia pc and hs. The stock supply is a 6 oz bottle. a. How many mL will you give for one dose? b. When will you give the Milk of Magnesia? c. How many total doses will be given in 1 day a. C. 7. The doctor has ordered Dopamine 3mcg/kg/min IV. You have an IV bag with 400 mg Dopamine in 200 ml D5W. The drop factor is 15 gtts/ml. The patient weighs 150 lbs. a. What is the flow rate in ml/hr? b. What is the flow rate in gtts/min? c. How many mg will the patient receive in 1 hour? b. a. C. b. C. 8. The doctor has ordered Ampicillin 750 mg. in 100 ml D5W to run over 30minutes q 6hr. The stock supply is a 1g vial with instructions to reconstitute with 4.5 ml NS for a final volume of 5 ml. The drop factor is 15 gtts/ml. a. How many ml will you add to the D5W for the correct dose? a. b. How many grams will the patient receive in 24 hours/ c. What is the flow rate in gtts/min? b. 9. The doctor orders 1000ml D5W IV to run over 12 hours. She also…Receptor 8.0 1 Drug A Receptor 7.8 2 Receptor 3 Drug B 8.5 PA value 5.2 6.4 Drug C 3.1 Drug D 6.5 10.5 3.9 6.5 4.5 9.7 Drug E 9.9 7.2 3.5 Which of these drugs is most likely to cause side-effects?CASE ANALYSIS: Toby is a 41-year-old patient who has cryptogenic partial epilepsy. He experienced his first seizure at age 14 and this was diagnosed as a secondary generalised attack, although discussing his history revealed he might have had complex partial seizures. Two years ago Toby was referred for assessment but it was felt that he was not a candidate for surgery. Toby was taking carbamazepine 1200mg a day and could not tolerate higher doses. Previous trials of valproate, phenytoin, phenobarbital, vigabatrin, lamotrigine, oxcarbazepine and topiramate had demonstrated little benefit. Levetiracetam was started and increased to 2500mg. Improvement in seizure control has been noted over the past 2 years with only two nocturnal complex partial seizures recorded. His current medication is levetiracetam 2500mg/day and carbamazepine 1200mg/day. DRUG THERAPY MANAGEMENT: GENERIC NAME BRAND NAME DOSAGE/ FORM FREQUENCY INDICATION FOR THE PATIENT MONITORING PARAMETERS…