12. Answer ALL parts of this question Cancer contributes to about a quarter of deaths in the UK every year. Our immune system has developed mechanisms for fighting cancer, and although a lot of emphasis is put on the adaptive immune system, the innate immune system plays an important role. (a) Describe the mechanisms of action of two of the innate cell types involved in fighting tumours (6 marks) (b) Describe three pieces of evidence that have demonstrated the importance of natural killer cells in fighting cancer. (၁) (3 marks) Describe how the innate immune system activates the adaptive immune system in fighting tumour cells. (11 marks)

12. Answer ALL parts of this question Cancer contributes to about a quarter of deaths in the UK every year. Our immune system has developed mechanisms for fighting cancer, and although a lot of emphasis is put on the adaptive immune system, the innate immune system plays an important role. (a) Describe the mechanisms of action of two of the innate cell types involved in fighting tumours (6 marks) (b) Describe three pieces of evidence that have demonstrated the importance of natural killer cells in fighting cancer. (၁) (3 marks) Describe how the innate immune system activates the adaptive immune system in fighting tumour cells. (11 marks)

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter45: The Immune System: Internal Defense

Section45.2: Innate Immune Responses In Vertebrates

Problem 3LO: Describe innate immune responses, including physical barriers; recognition by pattern recognition...

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2015.01 ImmunologY Intercept, processing, and presentation of Ag bone marrow hematopoietic stem cells On cytokines secreted by Th2 to activate 8 cell proliferation secreted on exposure to allergen, e.g. pollen is also an endogenous pyrogen, Le. stimulates hypothalamus to increase body temperature secreted by Te to "kill" target cells secreted by Th to activate Th1 response (CMI) 1 2 3. 4 5. IL-1 IL-2 Cytotoxin/porin Histamine IL-5