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- List the following in increasing order of nucleophilic strength. CH3COO-, H2O, CH3O-, OH-, CH3CH20-can you explain how can we determine major and minor product from these reaction elimination-addition? &=&=1561=6, NH₂ majo CH, NH₂ NH₂ &=-&-&-& majo CH3 OCH, CI NINH, NH 3liq. KNH₂ NH309. Br ΚΝΗ, NH CI CH₁ 80 80 OCH, majo NH, NH₂ mino CH3 mino NH₂ NH₂ NH, NH, CI majo CH3 majo NH₂ NH₂Arrange the compounds below in order of increasing reactivity in a SN2 reaction. 1. (CH3)2СНCI 2. CH3CH2B1 3. CH3CH2C1 A) 1; 2; 3 В) 3;B 2; 1 C) 1; 3; 2 D) 2; 1; 3 E) 3; 1; 2
- Determine the mechanism of nucleophilic substitution of each reaction and draw the products, including stereochemistr CH₂CH3 CI Br + CN d. + CH3COOH a. acetone + -OCH3 e. DMF f. b. C. ||||| a ||||| Br H Br CH2CH2CH3 + CH3OH DMSO H CH3 CI Br + OCH₂CH3 + CH3CH₂OHI H Ph Br In an E2 elimination reaction, the leaving group and the hydrogen atom must be anti-coplanar for this concerted reaction to occur. ||| Identify which of the following structures has the hydrogen atom and the leaving group aligned anti-coplanar. CH3 Ph Ph H TI F H || OH H Ph H CH3 CH3 Br Ph Br A) I B) II C) IIIHere is the same figure as in the previous two questions, but omitting the red circles. Cys157 Cys157 Cys157 His296 His296 His296 LOH HN HN HN N? -CO2 CH2 Asn329 Asn329 Asn329- Cys157 His296 LOH HN H HyC. Asn329 Which of the following roles is played by the imidazole side chain of His296? Pick the one best [ Select ] answer.
- Arrange the following compounds from least reactive to most reactive toward nucleophilic addition. 1 AI > III III >> A > | > Ilo II III H IVPredict whether the following nucleophiles are excellent nucleophiles, good nucleophiles, or poor nucleophiles based on their structure, and sort them accordingly.My Home OWLV2 | Online teaching and lear X G D /ilrn/takeAssignment/takeCovalentActivity.do?locator=assignment-take IReviaw Toples Draw structures for the carbonyl electrophile and enolate nucleophile that react to give the enone below. You do not have to consider stereochemistry. Draw the enolate ion in its carbanion form. Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right comer. Separate multiple reactants using the + sign from the drop-down menu. aste [F ChemDoode Submit Anewer Retry Entro Group 8 more group attempts remaining
- 3) Complete the following: Stereochemistry and regiochemistry may be important. b) d) type type MeO Br type type type OH H Br E1 Reaction Borohydride Reduction H NaOAc DMF Асон HO PCC CH₂Cl2 H CO₂Et f) g) h) i) j) type type type type type OH OH Hydride Reduction MeHN Reductive Amination HO Br OHRank thr stability of the following sets of reaction intermediates.Rank these nucleophiles from best to worst Na-I I Best (11)>(1)>(III) worst Best (1)>(III)>(II) worst Best (1)>(II)>(III) worst Best (III)>(1)>(1) worst None of these H₂C- II HạC—NH2 III