5.) A man and a woman living in a tropical area where malaria is prevalent and health care is not accessible have seven children during their lifetime. The genotypes of their children are: ss, Ss, SS, ss, Ss, Ss, and SS. What must the genotypes of both parents be? Your answer should include a Punnett square to illustrate your work, and list all the genotypes and phenotypes. 6.) In the previous problem, which of their children would you expect to live to adulthood and reproduce? Explain.
Q: 1. In chickens BB calls for a black chicken. WW calls for a white chicken. The BW combination calls…
A:
Q: Individual 1-3 is genotype 0 AA + 1 Aa + 0 aa Individual Il-4 is genotype 1/3 AA + 2/3 Aa + 0 aa…
A: Autosomal diseases are caused by mutations in the autosomes and the disease is recessive if the…
Q: Dihybrid In rabbits, grey hair is dominant to white hair. Also in rabbits, black eyes are dominant…
A: Sir Gregor Johann Mendel framed Mendel's Laws of Inheritance in order to simplify genetic studies.…
Q: What is the probability of producing a child with Down syndrome and show your solution
A:
Q: P1 F1 F2 1. Line 1 with pisatin 3 with pisatin X resistant 1 no pisatin www 2. Line 2 X resistant no…
A: Homozygous The condition in which the sets of gene are same either recessive or dominant.
Q: Identify the genotypes of the following individuals: Individual Genotype II-1 II-2 II-4…
A: Blood Group is basically an example of multiple Allele in which many alleles are involved . In…
Q: Some people with Turner syndrome are 45,X/46,XY mosaics. Explain how this mosaicism could arise.
A: Chromosomes are long thread-like structures that carry coded genetic information in the form of DNA.…
Q: In recent years, the country of Zambia in Africa has had increasing cases of malaria. If 9% of the…
A: In the Hardy-Weinberg equilibrium, the allele frequency and the genotype frequency of the…
Q: Imagine that you are a genetic counselor, and a couple planning to start a family comes to you for…
A: During gamete formation, two alleles of a gene segregate into different gametes. This is based on…
Q: You are making a genetic map and use a cross to measure the distance between genes H and J as…
A: A physical genetic map shows relative distance between genes on a chromosome.
Q: . Why is the relationship P=p2 used for homozygous loci?
A: Introduction :- Homozygous for a given locus refers to diploid and polyploid cells that have the…
Q: A certain couple has six children – four boys (ages 2yr, 5yrs, 9yrs and 11yrs old) and two girls…
A: Duchenne Muscular Dystrophy (DMD) is an X-linked recessive disorder that mainly affects male…
Q: 9. What is the probability that each of the following pairs of parents will produce the indicated…
A: Introduction: Mendel has given the law of independent assortment which says that during the transfer…
Q: Duchenne muscular dystrophy is sex linked and usuallyaffects only males. Victims of the disease…
A: Duchenne muscular dystrophy is an X-linked recessive disorder. Males have an XY chromosomal pattern,…
Q: 1. Using the correct allele notation, write the genotypes for Queen Victoria and Count Chocula. 2.…
A: (Kindly note that, you have uploaded two questions together, we can only able to answer one question…
Q: 1. Use the below pedigree chart to answer the following questions about dimples. The Dimple gene…
A: Introduction :- In genetics, dominance refers to the phenomenon of one gene variant on one…
Q: 1. For each genotype below, indicate whether it is a heterozygous (He) OR homozygous (Ho). TT Bb DD…
A: Genes are the functional unit of heredity. They are transferred from one generation to another.…
Q: Given the karyotype shown here, is this a male or a female? What would the genotype/phenotype of…
A: Karyotyping is the method of pairing and ordering all of an organism's chromosomes, resulting in a…
Q: 30. If the father has blood type AB, the mother has blood type B, a child with blood type A which of…
A: ABO blood grouping is an example of multiple allele; as more than two different forms of a given…
Q: What is the probability that the following cross will produce an organism homozygous recessive for…
A: One probability rule that's very useful in genetics is the product rule, which states that the…
Q: 14a. Colorblindness also results from an X-linked recessive allele. A color-blind man married a…
A: Answer: X-linked recessive disorder is the type of chromosomal inheritance which is transferred by…
Q: 23. Which of the karyotypes shown is from a normal female? (LS3-1) * A 10 11 10 15 10 17 88 88 8 88…
A: Chromosomes are thread-like structures present inside the nucleus of the cell. They are made up of…
Q: 1. a. Examine the following image showing the results of an ALU insert gel-like. The first lane is…
A: Introduction :- Alu insertions, which are unique to primates, are 300-bp bipartite interspersed…
Q: The first genetic test used a short DNA sequence that was closely linked to the Huntington’s locus.…
A: The linkage distance correlates with the percentage of recombinants produced as a result of crossing…
Q: 4. (1) How many females and males are affected in this pedigree? (2) Who is the proband? II (3) How…
A: NOTE-"As per our honor code, we are authorized to answer only one question at a moment. As you have…
Q: An individual comes into your genetics clinic to be tested for any anomalies. When looking at their…
A: Given: An individual come to your genetics clinic to be tested for any anomalies.When looking at…
Q: Cystic fibrosis is an inherited recessive disorder that causes especially thick mucus to build up in…
A: Cystic Fibrosis is a rare fatal genetic disease. It causes built up of thick mucus in the lungs,…
Q: ? ? 1.What are the genotypes of II-3 and II-5? Explain your reasoning using complete sentenc
A: X-linked receives inheritance consist of affect genes such as XdXd and XdY and the unaffected…
Q: “Cystic fibrosis is an autosomal recessive disease that affects the entire body. It also results in…
A: Since you have asked multiple questions, we will solve the first question for you. If you want any…
Q: A woman has the ABO genotype AO. A man has the ABO genotype BO. What are the possible phenotypes for…
A: Sir Gregor Mendel was a priest and a teacher who did the famous hybridization experiment on garden…
Q: 1.If the AaBBCc individual will be test-crossed, what is the probability that the resulting…
A: Alleles are also known as allelomorphs, are variants of a gene. They can be present in a dominant or…
Q: 2. How many loci are required by the FBI to positively identify an individual? Is it reasonably…
A: The accepted number of loci by Federal Bereau of Investigation is 13 which serves as standard of…
Q: In humans, brown eyes are dominant over blue eyes. If a couple who are both heterozygous for brown…
A: Heterozygous A zygote is formed by fusion of two different types of gamete carrying different…
Q: r rr rr Which best describes the parent genotypes in the punnet square provided?
A: Genetic inheritance is the passage of genetic information or Genetic character from the parents to…
Q: 15ITA
A: A karyotype is the chromosomal analysis of a single organism in which geneticists arrange…
Q: f any of the karyotypes below represent one of those syndromes, indicate the name of the syndrome.…
A: A karyotype is the arrangement and display of chromosomes in a tabular manner. The study of…
Q: 2. Draw a Punnett square of a cross between a homozygous dominant individual and a heterozygous…
A: Answer 1: - Parent individuals: - BB (homozygous dominant), Bb(heterozygous dominant) Cross: -…
Q: DNA sequencing of your own two β-globin genes (one from each of your two Chromosome 11s) reveals a…
A: I should be worried since presence of an abnormal beta globin chains may be an early indicator of…
Q: 28. Which of the following statement is incorrect A. Not all organisms with the same genotype look…
A: Answer :- Option (C) is correct. - Phenotypes result from the expression of an organisms genes as…
Q: A man and a woman living in a tropical area where malaria is prevalent and health care is not…
A: The disease is known as the disorder of some structures and functions of living organisms. This does…
Q: Examine the following karyotypes and answer the questions about each karyotype in the table below.…
A: Chromosomal abnormalities can occur due to non-disjunction i.e. a pair of chromosomes fails to…
Q: 29) With the below image, tell me what phenotype you would expect for the person on the eft? The…
A: PTC trait -- Introduction --PTC is the most commonly used for experiments There are many ways for…
Q: 1. What are the expected proportions in the offspring? You will need to propose which trait is…
A: According to Mendel's Law of inheritance: law of segregation : Each individual possesses two factors…
Q: 16.A couple is suspecting that their baby was switched at the hospital. The mother has blood type A,…
A: For this question we need to discuss co-dominant nature of blood group alleles. Blood group is…
Q: 2. 235O 4) Q7. Haemophiliacs possess a non-functional form of the gene responsible for the…
A: Haemophilia is a disease in which blood clotting does not occurs easily due to some missing clotting…
Q: Answer the questions about allele transmission for the below pedigree. Gen I X1x4 X3X3) Gen II X1x3…
A: The pedigree chart depicts the family tree and helps to reveal the family members who are affected…
Q: With the aid of annotated diagrams differentiate between incomplete dominance, complete dominance…
A: Since we only answer 1 question in case of multiple question, we’ll answer the first question as the…
Trending now
This is a popular solution!
Step by step
Solved in 2 steps with 1 images
- Sickle cell hemoglobin DNA CACGTAGACTGAGG ACAC.. Sickle cell hemoglobin MRNA Sickle cell hemoglobin AA sequence 4. What type of mutation is this? Please explain why.Correct answers already provided! Please don't just tell me the answers bc I know them already. Help me with my own question. I get everything else in this problem other than the third option: Introduce the mutant human HD allele as a transgene into the mouse genome with transgene integration anywhere in the mouse genome. Why is the first question (left) okay with introducing mutant human HD allele and the second question (right) is not? I heard that introducing allele without using CRISPR-Cas9 is very rare and difficult. If so, how does it work in the first problem (Hungtinton's chorea)?FINALLLY FRIDAY Part B: How Mutations Can Lead to Disorders Note: The examples given in this octivity do not represent exact DNA sequences on the genes described. To do so would be impossible as most genes contain over 1000 nucleotides that code for several hundred omino acids which are joined together to form proteins. This activity gives small segments of DNA in each of these genes and DOES demonstrate actual mutations that do occur within them. Gene 1. Beta Hemoglobin Gene (HBB Gene) is an important gene located on human chromosome 11 shown below. This gene plays an important role in the production of hemoglobin, a protein in red blood cells responsible for carrying oxygen in your blood. Part A: Normal Beta Hemoglobin: Using the un-mutated DNA sequence supplied from the HBB gene below, transcribe and translate the DNA into the corresponding arnino ack sequence that forms hemoglobin. NORMAL H866 GENE MUTATED HBB GENE DNA RNA DNA RNA H 1 C C 2 3 11 S 2 3 Chromosome 11 6 7 56 TGAGCT 03…
- Give only typing answer with explanation and conclusion A healthy asymptomatic 27 year old female, Susan, presents to your clinic with known family history of Spastic Paraplegia 4 caused by pathogenic SPAST mutation identified in her mother. She wants to know the risk that she will develop symptoms eventually based on this information. the penetrance of SPAST mutation is approximately 85% for women and 96% for men.33. Band 3 protein exists as a 95-kDa multipass membrane protein that functions as the primary anion exchanger in erythrocytes. Within the red blood cell (RBC) membrane, band 3 binds to spectrin dimers and tetramers indirectly through ankyrin. The spectrin tetramers are bound together by actin and band 4.1 protein, which also binds to band 3 and glycophorin. Null mutations in band 3 occur in the human population. Which one of the following is most likely to decrease in the absence of band 3 protein? a. Osmotic fragility b. Destruction of RBCS in the spleen c. Bile production d. Erythroid production in the bone marrow e. Blood pHQuestion: Some scientists have concluded that this method of gene therapy will be a more effective long-term treatment for SCD than HSCT. Use all the information provided to evaluate this conclusion. I dont know how to answer this question pls help:(
- BL1250 Group activity 4 2020 (1) – Saved to my Mac v Mailings Review View Tell me EXERCISE 4 QUESTIONS 1. TRANSCRIPTION: Much research effort has been invested in understanding how transcription is regulated, because this process is very important for determining cell function. Transcription is a major on/ off switch for genes, providing the instructions for translation and determining the types and amounts of proteins made in a cell at a specific time. The Zebrafish is a model organism for research, and many biologists study how the regulation of genes affects the development of the zebrafish embryo. The effects of a variety of experimental conditions on zebrafish embryos can be easily visualized by light microscopy, because the outer covering (chorion) and the embryo are both transparent. See an images of zebrafish embryos at different time points in development and the adult form below. 0h Os 0.75 h 2h 3.25 h 8 h 16 h 24 h 72 h Adult -3 months (not to scale) Image from:…For the following diseases, describe the best technique for diagnosing them. Please make sure you include how you would tell someone with the disease from someone without the disease. B. Factor V Leiden thrombophilia is caused by a point mutation at position 1691 in exon 10 of the Factor V clotting factor gene that changes an arginine into a glutamine. This change removes one of the cleavage sites for activated protein C and leads to an increased tendency to clot.b. Which one of the following a cell mutants will be able to switch at least once? [Select]
- Question 1 options: The specificity pocket of the serine protease chymotrypsin, which interacts with Tyr and Phe-containing peptide sequences, contains a Ser residue. A research group is trying to modify chymotrypsin such that it has a low KM with Trp-containing peptides. Enter the name or abbreviation of an amino acid that the Ser could be mutated to that would likely have the desired effect. (Hint: look at the diagrams of the specificity pockets shown in the course slides, and consider how the Ser would need to change to account for the difference between Tyr/Phe and Trp.)Question. Rewrite the following sentences after correction. (Subject: Biotechnology) The variation in the length of tandem repeat of microsatellite DNA has serious translational affects as this is due to its coding region. Correct: If one parent has sickle cell anemia and other has carrier genotype than there is 25 % chance that any offspring is carrier. Correct: Sickled WBC block the flow of blood and Calcium as they stick together and caused by frame shift mutation. Correct: The N1303K mutation in the CFTR gene of CF patients is autosomal dominant disorder due to insertion of asparagine at 1303. Correct: If a person RBCs have B surface antigen and it will clump with antigen B such clumping indicates Blood type B. Correct: Indirect ELISA can detect polygenic gene expression. Correct:Drug 1-Ivacaftor (VX-770): Ivacaftor is a potentiator that increases CFTR channel opening time. We know from cell culture studies that this increases chloride transport by as much as 50% from baseline and restores it closer to what would be expected in wild type CFTR. Basically, the drug increases CFTR activity by unlocking the gate that allows for the normal flow of salt and fluids. For which class of mutations do you think Ivacaftor will be most effective? Explain your choice.