6. The pedigree below traces the inheritance of a particular disorder. Circles are females, squares are males. Shaded symbols are affected with the disorder (NOTE: "half-shaded" symbols are NOT used here, for heterozygous individuals). What is the mode of inheritance of this disorder: is it dominant or recessive? Autosomal or X-linked? What is the genotype of the three numbered individuals? 1 2. 3.
Q: 3. Construct a pedigree chart by following the information given below. A man who is heterozygous…
A: Since you have asked multiple questions, we will solve the first question for you. If you want any…
Q: 1. What are some of the medical applications of karyotyping? 2 What kind of chromosomal aberration…
A: Genetic abnormalities are conditions caused by changes to the genes or chromosomes. Inherited…
Q: 6. Look at the following pedigree for a given trait to answer the questions below. || 1 B A KEY: O I…
A: According to Bartleby guidelines, only the first three have been answered. Kindly post the remaining…
Q: 5. Consider the following pedigrees. Each represents inheritance of a recessive phenotype. Explain…
A: Pedigree analysis is the diagrammatic representation which represents family history of individuals…
Q: please answer questions 4 a, b, c, and d.
A: A) The possible gametes of both the parents are BW, Bw, bW, and bw.B) The Punnett square showing the…
Q: hapsburg jaw/lip?
A: A Hapsburg jaw is a specific facial deformity that is marked by a very elongated and prominent lower…
Q: 7. In man, normal pigmentation is due to a dominant allele "A" and albinism to its recessive allele…
A: Albinism is an autosomal recessive disorder that results in little or no production of a pigment…
Q: 9. The pedigree below shows the occurrence of Becker muscular dystrophy in a family. Becker muscular…
A: A pedigree refers to the visual representations of the genetics of a family in the form of a family…
Q: 6. Identify the mode of inheritance for the following pedigree. Provide the genotypes of indicated…
A: In human genetics, the pedigree analysis is crucial when we analyze the inheritance pattern of genes…
Q: 3. Construct a pedigree chart by following the information given below. A man who is heterozygous…
A: The constructed pedigree along with genotypes are attached below. "a" allele carries the trait.
Q: What is example of sex-linked inheritance? Give also its definition
A: Sex linked traits are found on either one of the chromosomes that determine sex or sex chromosomes.…
Q: 4. The couple shown by the pedigree shown below, have 2 children, 1 girl with the disease and 1 boy…
A: X linked recessive trait is the type of trait that is inherited by the female child only if both the…
Q: 2. Assuming complete penetrance, which type of inheritance pattern is consistent with the pedigree…
A: Pedigree is a diagrammatic representation of either phenotypes or genotypes of a particular organism…
Q: 2. Lucy has fair (light) skin, red and wavy/curly hair. Use the model of her parents' genes above to…
A: The process of inheritance involves the transmission of genetic information from parents to progeny.…
Q: 1. 4. 6. Which mode(s) of inheritance could be RULED OUT for this smaller version of the previous…
A: The genes can de be differentiated into autosomal and sex-linked depending on their location. The…
Q: 6 What is the most likely mode of inheritance in the pedigree depicted to the right? a. Fully…
A: Genetics is the study of inheritance from parents to offspring to understand how genetic information…
Q: 1) Symptoms of 4 disorders are listed. Using the lists given, fill in the correct letter for the…
A: Inheritance is a mechanism of the characters, behaviors and traits that are by the another class…
Q: 2(a) Red-green color blindness is inherited as a recessive X-linked trait. What is the probability…
A:
Q: sex-linked inheritance? Give 3 examples.
A: Answer Sex-linked inheritance is the appearance of a trait which is due to the presence of an allele…
Q: 1. What is a pedigree? 2. In a pedigree chart, how would you know if the individual manifesting the…
A: The pedigree analysis involves the development of a kindred that may be accustomed trace the…
Q: Muscular dystrophy is a sex-linked recessive condition. If a woman who does not have the conditions…
A: Muscular Dystrophy(MD) It is a group of rare inherited muscle diseases in which muscle fibres are…
Q: 5. If a protein called phenylalanine builds up in the body, the person has a disease called…
A: INTRODUCTION Phenylketonuria This defect is caused due to the damage in the gene which produce…
Q: 3a. Based on the pedigree below, what is the most likely form of inheritance for the genetic…
A: Pedigree analysis is the study of the inheritance of genes in humans. It helps in identifying…
Q: 1. Miguel wants to know if his musical talent comes from his great-great grandfather Hector. When…
A: Hello. Since you have posted multiple questions and not specified which question needs to be solved,…
Q: please answer questions d, e, f, and g.
A: The branch of biology that deals with the study of genes, heredity and genetic variations are termed…
Q: 2. In humans, the gene for red-green color vision is located on the X chromosome with no…
A: Genetic inheritance is the process of passing of genetic information from parents to their progeny…
Q: 6. A pedigree is a useful tool for determining human inheritance patterns. Use the pedigree below to…
A: The inheritance of a character or a particular phenotype from parent to progeny due to the presence…
Q: 6) For the pedigree shown below, answer the following questions. I II II I a) What type of…
A: Pedigree analysis helps us identifying the mode of inheritance of a particular disease by observing…
Q: a. incomplete dominance b. overdominance c. co-dominance
A: Mendel has observed three types of dominance in the plant. Incomplete dominance is which the…
Q: 8. This family pedigree follows a family afflicted by a trait determined by the R gene IdA 2 9 10 11…
A: A gene is a unit of genetic material and alleles are the alternative form of genes present at the…
Q: 1. Define these three terms: a. trait – b. heredity - c. genetics - 2. What are alleles? 3. What is…
A: gene– the unit or heredity occupying a particular location on the chromosome and passed on to…
Q: 1. Draw the pedigree for Amita's family and determine the mode of inheritance if any. 2. Explain how…
A: From the given data, it is clear that the disease is autosomal, not sex-linked. As if it was…
Q: 4)If an individual is bald, so you can't tell whether or not they have a widow's peak, but neither…
A: A widow's peak is defined as a V-shaped point present in the hairline in the center or middle of the…
Q: 2. Identify the type of trait(s) in the pedigree below * autosomal recessive autosomal dominant…
A: Inheritance pattern is a pattern which determines how the genes are inherited from parental…
Q: 1. Use the below pedigree chart to answer the following questions about dimples. The Dimple gene…
A: The genotype of a cell or organism is the genetic code of that cell or organism. The sum of all…
Q: 5. For each of the following pedigrees, indicate whether the pattern of inheritance is recessive or…
A: Given, are two pedigree charts. Pedigree charts display a family tree which shows the members of the…
Q: 5. A man with a specific unusual genetic trait marries an unaffected woman and they have four…
A: X-linked disorders are those diseases in which the mutated genes are present on the X chromosomes…
Q: Pedigree 3: NOTE: the asterisk (*) indicates that the individual does not have any disease-related…
A: "Genetics" is the study of the functioning and main codes of variation and heredity. Inheritance is…
Q: 1. Red-green colorblindness is caused by a recessive allele (X) at an X-linked gene, and albinism is…
A: The most prevalent type is red-green colour blindness, followed by blue-yellow colour blindness and…
Q: 1. In humans, the allele for normal blood clotting, H, is dominant to the allele for hemophilia, h.…
A: Introduction: Haemophilia is an inherited genetic disorder that impairs the body's ability to…
Q: The last Emperor of Russia, Nicolas II, was married to Empress Alexandra , and they had five…
A: Family history is important to recognize the mode of inheritance of various diseases. Pedigree…
Q: А в F C D E H G J K L
A: B, C, H, J, L will all be carrier.
Q: 1. Red-green colorbilindness is caused by a recessive allele ) at an X-linked gene, and albinism is…
A: Mendelian factor is the unit of inheritance which passes from parent to offspring through gametes.…
Q: 1. In humans, normal pigmentation is due to a dominant gene A. Albinism is due to the recessive…
A: Albinism is an autosomal recessive disease. The presence of homozygous recessive genotype encodes…
Q: 1. In the pedigree below, Use "A" for the allele associated with the dominant phenotype, and…
A: A pedigree chart shows the inheritance pattern of a particular trait. Each row contains the…
Q: 9. Explain, giving reasons, whether the following pedigrees are compatible with autosomal dominant,…
A: Answer : autosomal dominant The disease is present in the parents and there is no skip in the…
Q: 1. A man with a rare genetic trait marries an unaffected woman and they have four children (first…
A: Father is affected and mother is unaffected. Mother is neither a carrier nor is affected by the rare…
Q: 4. What mode of inheritance is shown in the pedigree chart on the left? Justify your answer. 5.…
A: Pedigree is a branching representation indicating family members of everi generation . Pedigree…
Q: In a pedigree analysis a family shows a possible autosomal recessive inheritance, however karyotype…
A: Different tools are employed to study various fields of genetics. A knowledge of parentage, the…
Trending now
This is a popular solution!
Step by step
Solved in 5 steps with 3 images
- A heterozygous individual has a _______ for a trait being studied. a. pair of identical alleles b. pair of nonidentical alleles c. haploid condition, in genetic termsA couple was referred for genetic counseling because they wanted to know the chances of having a child with dwarfism. Both the man and the woman had achondroplasia (MIM 100800), the most common form of short-limbed dwarfism. The couple knew that this condition is inherited as an autosomal dominant trait, but they were unsure what kind of physical manifestations a child would have if it inherited both mutant alleles. They were each heterozygous for the FGFR3 (MIM 134934) allele that causes achondroplasia. Normally, the protein encoded by this gene interacts with growth factors outside the cell and receives signals that control growth and development. In achrodroplasia, a mutation alters the activity of the receptor, resulting in a characteristic form of dwarfism. Because both the normal and mutant forms of the FGFR3 protein act before birth, no treatment for achrondroplasia is available. The parents each carry one normal allele and one mutant allele of FGRF3, and they wanted information on their chances of having a homozygous child. The counsellor briefly reviewed the phenotypic features of individuals with achondroplasia. These include facial features (large head with prominent forehead; small, flat nasal bridge; and prominent jaw), very short stature, and shortening of the arms and legs. Physical examination and skeletal X-ray films are used to diagnose this condition. Final adult height is approximately 4 feet. Because achondroplasia is an autosomal dominant condition, a heterozygote has a 1-in-2, or 50%, chance of passing this trait to his or her offspring. However, about 75% of those with achondroplasia have parents of average size who do not carry the mutant allele. In these cases, achondroplasia is due to a new mutation. In the couple being counseled, each individual is heterozygous, and they are at risk for having a homozygous child with two copies of the mutated gene. Infants with homozygous achondroplasia are either stillborn or die shortly after birth. The counselor recommended prenatal diagnosis via ultrasounds at various stages of development. In addition, a DNA test is available to detect the homozygous condition prenatally. What if the couple wanted prenatal testing so that a normal fetus could be aborted?A couple was referred for genetic counseling because they wanted to know the chances of having a child with dwarfism. Both the man and the woman had achondroplasia (MIM 100800), the most common form of short-limbed dwarfism. The couple knew that this condition is inherited as an autosomal dominant trait, but they were unsure what kind of physical manifestations a child would have if it inherited both mutant alleles. They were each heterozygous for the FGFR3 (MIM 134934) allele that causes achondroplasia. Normally, the protein encoded by this gene interacts with growth factors outside the cell and receives signals that control growth and development. In achrodroplasia, a mutation alters the activity of the receptor, resulting in a characteristic form of dwarfism. Because both the normal and mutant forms of the FGFR3 protein act before birth, no treatment for achrondroplasia is available. The parents each carry one normal allele and one mutant allele of FGRF3, and they wanted information on their chances of having a homozygous child. The counsellor briefly reviewed the phenotypic features of individuals with achondroplasia. These include facial features (large head with prominent forehead; small, flat nasal bridge; and prominent jaw), very short stature, and shortening of the arms and legs. Physical examination and skeletal X-ray films are used to diagnose this condition. Final adult height is approximately 4 feet. Because achondroplasia is an autosomal dominant condition, a heterozygote has a 1-in-2, or 50%, chance of passing this trait to his or her offspring. However, about 75% of those with achondroplasia have parents of average size who do not carry the mutant allele. In these cases, achondroplasia is due to a new mutation. In the couple being counseled, each individual is heterozygous, and they are at risk for having a homozygous child with two copies of the mutated gene. Infants with homozygous achondroplasia are either stillborn or die shortly after birth. The counselor recommended prenatal diagnosis via ultrasounds at various stages of development. In addition, a DNA test is available to detect the homozygous condition prenatally. What is the chance that this couple will have a child with two copies of the dominant mutant gene? What is the chance that the child will have normal height?
- A couple was referred for genetic counseling because they wanted to know the chances of having a child with dwarfism. Both the man and the woman had achondroplasia (MIM 100800), the most common form of short-limbed dwarfism. The couple knew that this condition is inherited as an autosomal dominant trait, but they were unsure what kind of physical manifestations a child would have if it inherited both mutant alleles. They were each heterozygous for the FGFR3 (MIM 134934) allele that causes achondroplasia. Normally, the protein encoded by this gene interacts with growth factors outside the cell and receives signals that control growth and development. In achrodroplasia, a mutation alters the activity of the receptor, resulting in a characteristic form of dwarfism. Because both the normal and mutant forms of the FGFR3 protein act before birth, no treatment for achrondroplasia is available. The parents each carry one normal allele and one mutant allele of FGRF3, and they wanted information on their chances of having a homozygous child. The counsellor briefly reviewed the phenotypic features of individuals with achondroplasia. These include facial features (large head with prominent forehead; small, flat nasal bridge; and prominent jaw), very short stature, and shortening of the arms and legs. Physical examination and skeletal X-ray films are used to diagnose this condition. Final adult height is approximately 4 feet. Because achondroplasia is an autosomal dominant condition, a heterozygote has a 1-in-2, or 50%, chance of passing this trait to his or her offspring. However, about 75% of those with achondroplasia have parents of average size who do not carry the mutant allele. In these cases, achondroplasia is due to a new mutation. In the couple being counseled, each individual is heterozygous, and they are at risk for having a homozygous child with two copies of the mutated gene. Infants with homozygous achondroplasia are either stillborn or die shortly after birth. The counselor recommended prenatal diagnosis via ultrasounds at various stages of development. In addition, a DNA test is available to detect the homozygous condition prenatally. Should the parents be concerned about the heterozygous condition as well as the homozygous mutant condition?1. In the pedigree below, Use "A" for the allele associated with the dominant phenotype, and lowercase "a" for the allele associated with the recessive phenotype. Determine what is the most likely mode of inheritance of this disease (whether it is inherited as the result of an autosomal dominant or autosomal recessive trait). Write the most probable genotype for each individual based on the mode of inheritance you have determined. Show how all the partners are crossed and the expected offspring produced (You may use Punnett Square) 1 dró || IV6. A person is simultaneously heterozygous for two autosomal genetic traits. One is a recessive condition foralbinism (alleles A and a); this albinism gene is foundnear the centromere on the long arm of an acrocentricautosome. The other trait is the dominantly inheritedHuntington disease (alleles HD and HD+). TheHuntington gene is located near the telomere of oneof the arms of a metacentric autosome. Draw all copies of the two relevant chromosomes in this person asthey would appear during metaphase of (a) mitosis,(b) meiosis I, and (c) meiosis II. In each figure, labelthe location on every chromatid of the alleles forthese two genes, assuming that no recombinationtakes place.
- 11. Below is a pedigree chart of an autosomal recessive disorder. Answer the following questions using the correct genetic terminology (do not just write letters like “Ee”). A. What is the genotype of individual 1 in generation II? B: What is the genotype of individual 2 in generation I?C: Is it true that individuals 6, 7, 8, 9, and 10 in generation III all have the same genotype? Why or why not?12. A. B. C. A certain type of migraine headache (M) is dominant to no migraines (m). What is the genotype of a man who has migraine headaches if his father did not have them? What is the genotype of a man who has migraine headaches if his mother did not have them? If a woman without migraines marries a man who is heterozygous for migraines, what would you expect for the genotypes and phenotypes of their children? If two people who are heterozygous for migraines marry and have children, what would you expect for the genotypes and phenotypes of the children.1 II 1 4 6. II 1 2 4 5 6. 8. IV The above image shows a pedigree for a monogenic inherited disease. Although this trait is only observed in males in this family, the pattern of inheritance of this disease is autosomal recessive. Use the pedigree to explain why the inheritance of this disease cannot be autosomal dominant. If this trait is X-linked recessive, what would be the genotypes of the people in Row I? 2. 2. 3. 2. 3.
- II. Given the following pedigree below, use Punnett squares for each of the following possibilities: a) X- linked dominant and b) X-linked recessive in order to determine what is the mode of transmission of this trait. Disease allele = XA or Xª, depending on mode of transmission of the disease respectively. *Unaffected/No carrier-Normal Unaffected X chromosome = X I || III 1 1 2 a) X-linked recessive 9 III 6 genotype (circle one): XX * 1 2 3 11x12 4 ΧΑΧΑ 2 5 xaxa *4 6 7 8 b) X-linked dominant 11 x 12 오 XAX хах1) Symptoms of 4 disorders are listed. Using the lists given, fill in the correct letter for the condition name and inheritance type. Letters may be used more than once. Symptoms Condition Inheritance Туре Loss of muscle control and decline in mental ability Shades of red and green are hard to distinguish Lack of skin pigmentation Cannot produce one of the necessary blood clotting factors Conditions: Inheritance Type: A: Albinism E: X-linked dominant B: Huntington Disease F: X-linked recessive G: Y-linked C: Hemophilia H: Autosomal dominant I: Autosomal recessive D: CVD8. Huntington’s disease is a degenerative disease of the nervous system that strikes in middle age. The allele that causes the disease (H) is dominant to the allele that results in the normal condition (h). Answer the following questions about the inheritance of this disease. A. What is the genotype of a man who is normal but whose father had Huntington’s disease? B. What is the genotype of a woman who has Huntington’s disease if both of her parents had Huntington’s disease? C. If a man who is heterozygous for Huntington’s disease marries a woman who is normal, what would you expect for the genotypes and phenotypes of their children? D. If a normal man marries a woman who is homozygous for Huntington’s disease, what do you expect for the genotypes and phenotypes of their children?