A group of students wanted to check the association between hypertension and high levels of LDL in patients. Below shows the contingency table that they got after collecting data from a certain number of people. With High LDL With Low LDL With Hypertension 87 36 Without Hypertension 48 123 Guide Questions: 1. Determine the Odds Ratio and Relative Risk and interpret their values a. Is High LDL a protective factor or a risk factor for hypertension? b. Does your answer in 1a) follow current trends in literature? (Please cite your references) 2. Discuss the results above and its implications a. Using Bradford Hill Criteria, is it suggestive for a causal association? b. What other criteria/further research would you recommend to strengthen the notion that High LDL would contribute to hypertension?

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A group of students wanted to check the association between hypertension and high levels of LDL in patients.
Below shows the contingency table that they got after collecting data from a certain number of people.
With High LDL
With Low LDL
With Hypertension
87
36
Without Hypertension
48
123
Guide Questions:
1.
Determine the Odds Ratio and Relative Risk and interpret their values
a. Is High LDL a protective factor or a risk factor for hypertension?
b. Does your answer in 1a) follow current trends in literature? (Please cite your references)
2. Discuss the results above and its implications
a. Using Bradford Hill Criteria, is it suggestive for a causal association?
b. What other criteria/further research would you recommend to strengthen the notion that
High LDL would contribute to hypertension?
Transcribed Image Text:A group of students wanted to check the association between hypertension and high levels of LDL in patients. Below shows the contingency table that they got after collecting data from a certain number of people. With High LDL With Low LDL With Hypertension 87 36 Without Hypertension 48 123 Guide Questions: 1. Determine the Odds Ratio and Relative Risk and interpret their values a. Is High LDL a protective factor or a risk factor for hypertension? b. Does your answer in 1a) follow current trends in literature? (Please cite your references) 2. Discuss the results above and its implications a. Using Bradford Hill Criteria, is it suggestive for a causal association? b. What other criteria/further research would you recommend to strengthen the notion that High LDL would contribute to hypertension?
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