A two-step pathway that is activated by the secretion of glucagon and adrenaline
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A two-step pathway that is activated by the secretion of glucagon and adrenaline
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- Process of exocytosis of insulinBreakdown of glycogen to release glucose.Under conditions of stress, the hormone glucagon is synthesized and secreted from the α-cells of the pancreas. Please describe how glucagon can regulate the activity of glycogen phosphorylase and explain how this affects energy expenditure in human body
- Why liver will use atp in fasting state to produce glucose however it is unable to use glucose as a fuel under those conditionsA certain type of tumor results in the overproduction of glucagon. Researchers claim that treatment with insulin can counteract the effects of the excess glucagon on the pathway shown in Figure 2. Provide reasoning to justify the researchers' claim.Diabetes mellitus is a set of metabolic diseases with the common symptom of an inability to transport glucose into target cells (muscle cells and adipocytes). The body compensates in part by degrading muscle protein to generate energy. Explain how this process works.
- Diabetes is a complex set of metabolic diseases with thecommon symptom of an inability to transport glucose intotarget cells (muscle cells and adipocytes). The body compensates in part by degrading muscle protein to generate energy.Explain how this process works.Cancer cells have a high amount of hexokinase. Explain why.true or false: Guanylate phosphorylase is responsible for converting guanosine monophosphate into guanosine diphosphate
- Epinephrine stimulates glycogen breakdown by activating glycogen phosphorylase. However, in the research lab, no glycogen breakdown occurred when epinephrine was added to a test tube containing the enzyme and its substrate, glycogen. Explain why glycogen phosphorylase could be activated by epinephrine only when the hormone was added to intact cells in a solution.Phosphoglucomutase is crucial for glycogen breakdown as well as for glycogen synthesis. Explain the role of this enzyme in each of the two processes.People with type 2 diabetes have cells that do not respond to insulin, explain the problem this causes and why that problem occurs (at the cellar level)