An analgesic drug, acetaminophen (MM = 151.16), was synthesized in the laboratory by reacting 3.25 g of 4-aminophenol (MM = 109.13) and 2.14mL of ethanoic anhydride (MM = 102.09). This reaction produced 3.40 g of crude acetaminophen which was subsequently purified by recrystallization yielding 2.95 g of pure crystals. p(ethanoic anhydride) = 1.08 g/mL. Table 1. Solubility of acetaminophen at different solvent At room temperature Upon cooling Solvent A B U D Insoluble Soluble Insoluble Insoluble On heating Soluble Soluble Soluble Insoluble Soluble Soluble Insoluble Insoluble NH₂ OH O O CH,C_O_CCH; -0- H-N-CCH₂ OH + CH₂C-O-H

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Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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An analgesic drug, acetaminophen (MM = 151.16), was synthesized in the laboratory by reacting
3.25 g of 4-aminophenol (MM = 109.13) and 2.14mL of ethanoic anhydride (MM = 102.09). This
reaction produced 3.40 g of crude acetaminophen which was subsequently purified by
recrystallization yielding 2.95 g of pure crystals. p(ethanoic anhydride) = 1.08 g/mL.
Table 1. Solubility of acetaminophen at different solvent
At room
temperature
Upon
cooling
Solvent
A
B
с
D
Insoluble
Soluble
Insoluble
Insoluble
On heating
Soluble
Soluble
Soluble
Insoluble
Which is the limiting reagent?
What is the theoretical yield?
What is the percentage yield?
What is the percentage recovery?
Soluble
Soluble
Insoluble
Insoluble
NH₂
OH
+
CH₂0-0-OCH,
O
H-N-CCH₂
OH
0
||
+ CH3C-O-H
Transcribed Image Text:zxwu.2016 An analgesic drug, acetaminophen (MM = 151.16), was synthesized in the laboratory by reacting 3.25 g of 4-aminophenol (MM = 109.13) and 2.14mL of ethanoic anhydride (MM = 102.09). This reaction produced 3.40 g of crude acetaminophen which was subsequently purified by recrystallization yielding 2.95 g of pure crystals. p(ethanoic anhydride) = 1.08 g/mL. Table 1. Solubility of acetaminophen at different solvent At room temperature Upon cooling Solvent A B с D Insoluble Soluble Insoluble Insoluble On heating Soluble Soluble Soluble Insoluble Which is the limiting reagent? What is the theoretical yield? What is the percentage yield? What is the percentage recovery? Soluble Soluble Insoluble Insoluble NH₂ OH + CH₂0-0-OCH, O H-N-CCH₂ OH 0 || + CH3C-O-H
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