An individual heterozygous for 3 genes, Aa Bb Cc are test-crossed to aa bb cc and 1000 progenies are classified by the gametic contribution of the heterozygous parent as follows: ABC-305 abc - 310 aBC - 42 Abc - 43 ABC -140 Abc - 145 aBc - 6 AbC - 9 Draw linkage map of the linked genes, showing the order and the distance in cM.

An individual heterozygous for 3 genes, Aa Bb Cc are test-crossed to aa bb cc and 1000 progenies are classified by the gametic contribution of the heterozygous parent as follows: ABC-305 abc - 310 aBC - 42 Abc - 43 ABC -140 Abc - 145 aBc - 6 AbC - 9 Draw linkage map of the linked genes, showing the order and the distance in cM.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter6: Cytogenetics: Karyotypes And Chromosome Aberrations

Section: Chapter Questions

Problem 24QP: A geneticist discovers that a girl with Down syndrome has a Robertsonian translocation involving...

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An Hfrstrain that is a *b*c*d* e*f* g *h* is mated with an F strain that is a b e d e f gh. The mating is interrupted at 5 minutes interval, and the genotypes of the F recombinants are determined. The results obtained are tabulated in Table 2. Draw the map of the Hfrchromosome and indicate the position of the origin of transfer, the direction of the transfer and the minutes between genes. Table 2:Entry time of Hfr chromosome into recipient cell. Time a d e f h 5 10 15 20 25 30 35 40 45 50 55 60 65 70 75 80 85 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
n corn, male sterility is controlled by maternal cytoplasmic elements. This phenotype renders the male part of the corn plants (i.e the tassel) unable to produce fertile pollen; the female parts, however, remain receptive to pollination by pollen from male fertile corn plants. However, the presence of a nuclear fertility restorer gene F restores fertility to male sterile lines Using the cardboard chips, simulate the crosses indicated below. Give the genotypes and phenotypes of the offsprings in each cross, and properly label the nucleus and the cytoplasm each individual in the cross Legend male sterile cytoplasm Male fertile cytoplasm FF nucleus Ff nucleus ff nucleus A. Male sterile female x FF male Explain the phenotype of the offspring B. Male sterile female x Ff male Explain the phenotype of the offspring
For questions 22 through 30, please refer to the pictures below: Normal B B B C D D D D' E E 22 23 24 B D G. Y D M H. B C E 25 26 27 28 B D Break through centromere B B A D 29 30 Identify the type of chromosomal aberration in each number above. Please refer to the choices below. Reciprocal translocation Robertsonian translocation Isochromosome Terminal deletion Interstitial deletion Duplication Pericentric inversion Ring chromosome Marker chromosome Paracentric inversion
3.27 Complementation tests of the recessive mutant g genes a through f produced the data in the accom- panying matrix. The circles represent missing data. beaim Assuming that all of the missing mutant combina- motions would yield data consistent with the entries ithat are known, complete the table by filling each oneel circle with a + or – as needed. - rt yd bat 21 igi a rıb a O + b c d e fi 612 nobsdi b liw insiqans bosale yns mon las 29 ni YOu C ono e 66 BA AA f AA
n corn, male sterility is controlled by maternal cytoplasmic elements. This phenotype renders the male part of the corn plants (i.e the tassel) unable to produce fertile pollen; the female parts, however, remain receptive to pollination by pollen from male fertile corn plants. However, the presence of a nuclear fertility restorer gene F restores fertility to male sterile lines sing the cardboard chips, simulate the crosses indicated below. Give the genotypes and phenotypes of the offsprings in each cross, and properly label the nucleus and the cytoplasm of each individual in the cross Legend male sterile cytoplasm Male fertile cytoplasm FF nucleus Ff nucleus ff nucleus A. Male sterile female x FF male Explain the phenotype of the offspring B. Male sterile female x Ff male Explain the phenotype of the offspring
A geneticist discovers that a girl with Down syndrome has a Robertsonian translocation involving chromosomes 14 and 21. If she has an older brother who is phenotypically normal, what are the chances that he is a translocation carrier?
The gene controlling ABO blood type and the gene underlying nail-patella syndrome are said to show linkage. What does that mean in terms of their relative locations in the genome? What does it mean in terms of how the two traits are inherited with respect to each other?
A yeast geneticist irradiates haploid cells of a strain thatis an adenine-requiring auxotrophic mutant, caused bymutation of the gene ade1. Millions of the irradiatedcells are plated on minimal medium, and a small number of cells divide and produce prototrophic colonies.These colonies are crossed individually with a wildtype strain. Two types of results are obtained:(1) prototroph × wild type : progeny all prototrophic(2) prototroph × wild type : progeny 75% prototrophic,25% adenine-requiring auxotrophsa. Explain the difference between these two types ofresults.b. Write the genotypes of the prototrophs in each case.c. What progeny phenotypes and ratios do you predictfrom crossing a prototroph of type 2 by the original ade1auxotroph?
The following results are derived from crosses between Neurospora strain xy and strain ++: Tetrad Class 3 4 ху x+ x+ xy ++ ++ ++ +y +y ху +y 25 ++ 3 124 4 (i) Name the ascus type of each class from 1 to 4 as P, NP or T. (ii) Are genes x and y linked? Explain your answer. (iii) If they are linked, determine the map distance between the two genes. If they are unlinked, provide all the information you can about why you draw this conclusion.
In an in situ hybridization experiment, a certain clonebound to only the X chromosome in a boy with no diseasesymptoms. However, in a boy with Duchenne musculardystrophy (X-linked recessive disease), it bound to theX chromosome and to an autosome. Explain. Could thisclone be useful in isolating the gene for Duchenne muscular dystrophy?
An individual is heterozygous for a reciprocal translocation, with the following chromosomes: A • B C D E F A • B C V W X R ST • U D E F R ST • U V W X Q. Explain why the fertility of this individual is likely to be less than the fertility of an individual without a translocation.
+ ec +/Y + + w/Y y ec +/Y + ec +/y ec w ++ w/y ec w у ес +у ес и Determine the order in which the three loci y, ec, and w Occur on the chromosome and prepare a linkage map. 7.22 A cross involving X-linked genes was made between yellow, bar, vermilion female fies and wild males, and the F1 females were crossed with y B v males. The following phenotypes were obtained when 1000 progeny were exam- ined: Dra ord ma the 7.2 546 244 160 50 + + + + Bv y Bv y+ + y+v y B+ and an and and and +B + re + + v ge Determine the order in which the three loci occur on the chromosome and prepare a linkage map. 7.23 Female Drosophila heterozygous for ebony (e"le), scarlet (st*/st), and spineless (ss*/ss) were testcrossed, and the following progeny were obtained: PROGENCY PHENOTYPES NUMBER ir Wild type Ebony Ebony, scarlet Ebony, spineless Ebony, scarlet, spineless Scarlet 67 8. 68 347 78 368 Scarlet, spineless Spineless (a) Are these genes linked? Justify your answer. (b) Write the genes given on a…