Back to Mr. Doe and his MRSA which over time is becoming more and more resistant to brincomycin. In the diagram below time is moving from left to right. Drag-drop the arrow-labels and the captions to describe how Mr. Doe's MRSA is evolving resistance to brincomycin. You only need to label one moment of diffusion, one pump and one molecule of brincomycin. Time 1 Time 2 Time 3 Efflux Pump brincomycin Diffusion into cell MRSA MRSA MRSA Efflux pump removes MRSA Efflux pump grabs brincomycin as fast as it diffuses in, cell MRSA antibiotic better, pumps it out faster, less brincomycin stays in cell MRSA Efflux pump grabs antibiotic inefficiently, pumps it out slowly, brincomycin stays in cell long enough to not damaged by the antibiotic What is happening: damage it MIC = 8 MIC MIC =1 MIC =2
Back to Mr. Doe and his MRSA which over time is becoming more and more resistant to brincomycin. In the diagram below time is moving from left to right. Drag-drop the arrow-labels and the captions to describe how Mr. Doe's MRSA is evolving resistance to brincomycin. You only need to label one moment of diffusion, one pump and one molecule of brincomycin. Time 1 Time 2 Time 3 Efflux Pump brincomycin Diffusion into cell MRSA MRSA MRSA Efflux pump removes MRSA Efflux pump grabs brincomycin as fast as it diffuses in, cell MRSA antibiotic better, pumps it out faster, less brincomycin stays in cell MRSA Efflux pump grabs antibiotic inefficiently, pumps it out slowly, brincomycin stays in cell long enough to not damaged by the antibiotic What is happening: damage it MIC = 8 MIC MIC =1 MIC =2
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter12: Body Defenses
Section: Chapter Questions
Problem 1ACR
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