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Based on your understanding, list down FIVE (5) important points regarding DNA methylation process in epigenetics mechanism.
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- Base on your knowledge of DNA, chromosomes and epigenetics and upon examining the picture below, name two epigenetic factors and at least one non-epigenetic factor present on this picture. [HINT: which of the factors shown on the picture do you expect to change based on the interactions with an environment and which you expect unchanged?] Methyl Group DNA Chromatin Epigenetic Factor Histone Histone Tails Chromosomehttps://ny.pbslearningmedia.org/resource/biot09.sci.life.gen.epigenetics/epigenetics/ Explain DNA methylation. How does this process influence cellular function?Briefly, be able to define each of these AND, where relevant, tell what do they do, and which process(es) are they involved in (for example, replication or translation or transcription or splicing etc.) * means can you draw it (stick figure)? *fork Genetic terms on test3 helicase heritability (broad vs. narrow sense) Hox genes Intercalating agent Kinetochore MRNA (eukaryotic) 3 processing steps nucleosome *nucleotide (what are its parts?) Okazaki fragment *operon PCR plasmid polyA polymerase polyploidy vs. aneuploidy *promoter proofreading purine pyrimidine QTL
- . Let’s say that you have incredible skill and can isolate the white and red patches of tissue from the Drosophila eyes shown in Figure 12-24 in order to isolate mRNA from each tissue preparation. Using your knowledge of DNA techniques from Chapter 10, design an experiment that would allow you to determine whether RNA is transcribed from the white gene in the red tissue or the whitetissue or both. If you need it, you have access to radioactive white-gene DNAOften, the physical characteristics of genetically identical twins become increasingly different as they age, even at the molecular level. Explain why this is so from the point of view of epigenetics.What epigenetic modification(s) would you expect to see near a gene promoter where transcription is occurring? Histone acetylation 2.)Histone methylation 3.)DNA methylation 4.) a&c 5.) b&c
- What are the mechanisms in which DNA is used to generate protein. The key points in the process and mention any major differences between the mechanism in prokaryotic and eukaryotic cells Although the DNA in our genes is considered to be the heritable genetic material, other factors, including the environment are considered to play an important role in the activity and expression of those genes; the role that epigenetics & developmental epigenetics play in health & disease.What are the mechanisms in which DNA is used to generate protein. What are the key points in the process and major differences between the mechanism in prokaryotic and eukaryotic cells Although the DNA in our genes is considered to be the heritable genetic material, other factors, including the environment are considered to play an important role in the activity and expression of those genes. Summarize the role that epigenetics & developmental epigenetics play in health & disease.(1)What is epigenetics? What is the role of methylation in epigenetics? At what level (Replication, Transcription, Translation) does epigenetics act? (2) What is the effect of splicing on RNA? What is the purpose of alternate splicing? (3) If a DNA sequence is 5' TCC GGT CAT 3' what are the RNA and protein sequences that can be made from the strand? Use this codon table บบบา UUC UUA UUG CUU CUC CUA CUG AUU AUC AUA AUG a GUU GUC GUA GUG. Phe Leu Leu lle Met Val UCU UCC UCA UCG CCU CCC CCA CCG ACU ACC ACA ACG GCU GCC GCA GCG Ser Pro Thr Ala UAU UAC UAA UAG CAU č} CAC CAA CAG AAU AAC AAA AAG GAU GAC GAG} Tyr Stop His Gln Asn Lys Asp Glu UGU UGC Cys UGA Stop UGG Trp CGU CGC CGA CGG AGU AGC AGA à} AGG GGU GGC GGA GGG Arg Ser Arg Gly 4. Normal yeast cells can survive on a diet of sugars, a few simple salts and one vitamin. They can make all of their amino acids and other vitamins using what can be found in their diet. You identify a mutant strain that can only survive if given alanine, which…
- List and briefly describe five types of molecular mechanisms thatmay underlie epigenetic gene regulation.DNA methylation is considered an epigenetic phenomenon because the pattern of methylation can be inherited. Briefly discuss the question of whether histone modifications in chromatin represent an epigenetic phenomenon.https://ny.pbslearningmedia.org/resource/biot09.sci.life.gen.epigenetics/epigenetics/ Explain how two genetically identical twins are not really identical.