Benzodiazepines are known to have a wide therapeutic window. What makes benzodiazepines relatively safe even when consumed in higher than therapeutic doses?
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- Benzodiazepines are known to have a wide therapeutic window. What makes benzodiazepines relatively safe even when consumed in higher than therapeutic doses?Why are some physicians are careless when prescribing benzodiazepines for patients suffering from severe anixety?Which five benzodiazepines are approved for hypnotic use?
- ¨ What other types of analgesics are on the market? How does their action compare with aspirin and why are these alternative drugs necessary? Discuss the differences among the following compounds by drawing their structures: Acetylsalicylic acid, Acetaminophen (Paracetamol), Ibuprofen, Paracetamol and Phenacetin.Why is acetaminophen often recommended in place ofaspirin?Discuss the chemistry of histamine, antihistamines, and anti-ulcer drugs
- True or False 1. Schizophrenia is a type of depression. 2. Antipsychotics act as dopamine antagonists. 3. TCAs can cause postural (orthostatic) hypotension and tachycardia. 4. Epinephrine is contraindicated in patients taking an SSRI. 5. The amount of EPI used in patients taking an antipsychotic should be minimized.What metabolic reaction is illustrated by the image below? * СООН СООН -OCOCH3 CH,COOH он + Ester hydrolysis Decarboxylation Nitro- reduction Deamination Azo reduction1. An inactive or much less active form of drug which transformed to active drug in the body is a. Coated drug b. Specialized dosage form c. Prodrug d. Reservoir 2. Sodium pump is an example of a. G-protein receptors b. Ion channels c. Gene Transcription linked receptor d. Enzyme-linked tyrosine kinase3. As the length of a non-polar chain of aliphatic alcohol increases, its solubility in water a. Increases b. Decreases c. No effect 4. More common force of attraction for drugs a. Covalent b. Electrostatic c. Hydrogen bonding d. Ionic5. In organs and tissues that are well-perfuse, drug distribution is a. Faster b. Slower c. Negligible d. The same
- How does Temazepam differ from Diazepam?Are you surprised that rivaroxaban and apixaban are both drugs that have the same function (anticoagulant)? Why?A patient has been prescribed a reducing dose of oral prednisolone tablets. "Prednisolone 25mg daily for 7 days then reduce by 5mg each week until finished" Prednisolone available as 5mg tablets. How many tablets should you dispense to allow the patient to complete the course?