Calculate the oral loading dose (LD) of digoxin for Miss Jones who weighs 60 kg. The desired plasma concentration (Cp) is 1.5 mcg/L, volume of distribution (Vd) is 7.3 L/kg, the salt factor (S) is 1 and bioavailability fraction (F) is 0.7. Give your answer to the nearest whole number of micrograms. The equation below can be used: Loading Dose = Cp desired x Vd S x F

Calculate the oral loading dose (LD) of digoxin for Miss Jones who weighs 60 kg. The desired plasma concentration (Cp) is 1.5 mcg/L, volume of distribution (Vd) is 7.3 L/kg, the salt factor (S) is 1 and bioavailability fraction (F) is 0.7. Give your answer to the nearest whole number of micrograms. The equation below can be used: Loading Dose = Cp desired x Vd S x F

Curren'S Math For Meds: Dosages & Sol

11th Edition

ISBN:9781305143531

Author:CURREN

Publisher:CURREN

Chapter20: Iv Medication And Titration Calculations

Section: Chapter Questions

Problem 27SST

See similar textbooks

Similar questions

Assume that Ali (same patient in question 1) was prescribed vancomycin 1000 mg every 36 hours. After few days, Steady-state vancomycin concentrations were obtained before and after the fourth dose, and the peak concentration (obtained ½ hour after a 1- hour infusion of vancomycin) was 34 µg/mL while the trough concentration (obtained immediately before dosage administration) was 2.5 pg/mL. Compute a revised vancomycin dose for this patient to provide a steady-state peak concentration of 48 ug/mL and a steady- state trough concentration of 17 pg/mL. a. Estimate new rate constant (Ke) and half-life (t1/2) b. Estimate volume of distribution (Vd) using this equation Cmaxss + Cminss C. Calculate the new dose interval d. Calculate the new dose
One general guideline for the maintenance dosing of heparin in pediatric patients is 100 units/kg every4 hours, or 20,000 units/m²/24 hour administered continuously. The a vailable injection for use by intravenous infusion contains 1000 USP Heparin Units/mL For a 44-lb child, measuring 42 inches in height, calculate the difference between the quantities of heparin administered over a 24-hour period in (a) heparin units, (b) in milligrams of heparin (sod ium), and (c) in milliliters of heparin injection.
KCI for injection contains 40 mEq in 20 mL. An order requires 15 mEq, how many mL are needed?
Compute for the loading dose of Gentamicin for a 135-pound patient if the target plasma concentration is 0.06mg/L. The hypothetical volume of distribution of the drug is 0.36L/kg body weight
An 84 year old male patient has been given a loading dose of digoxin of 298 micrograms in divided doses by intravenous infusion. He has a creatinine clearance (Ccr) of 34 ml / min. What is the maintenance dose (in micrograms) that this patient should receive? Round your answer to the nearest whole number. Use the formula provided to calculate the maintenance dose. Maintenance Dose = Peak body stores x % daily loss 100 Where: Peak Body Stores = Loading Dose % Daily Loss = 14 + Creatinine clearance (Ccr) 5
The erythrocyte sedimentation rate (heaviness) test of a blood sample is often used as a diagnosis of immune disorders and some other diseases. Assuming that the red blood cells are about a sphere with a diameter of (approximately 5 um) and a density (g/ml 1.125), and the density and viscosity of the plasma in which the red blood cells are settled (Pa.s), (1025 kg/m3 10-3 x 1.5) On arrangement and acceleration m/s2 9.81 Calculate the erythrocyte sedimentation rate (settlement rate).
Sarah who weighs 67 kg is to receive acetylcysteine at a dose of 50 mg/kg infused over 4 hours for paracetamol overdose. The required volume of concentrated acetylcysteine solution (200 mg/mL) has been added to 500 mL of 5% glucose solution. What is the concentration of the solution to be infused (mg/mL)? (Answer to 1 decimal place.) Answer: 16.75 mg x