Depression is a condition in which sufferers may feel low mood, lack of motivation and sleep. It is caused by a lack of serotonin in the synaptic cleft of neurone pathways. Serotonin is a neurotransmitter.   a) Describe how serotonin acts as a neurotransmitter. Using your understanding of synaptic transmission, explain how communication between neurones in serotonin pathways of the brain would be affected in someone with depression.   b) Doctors use tubocurarine drug as an anaesthetic as it temporarily paralyses muscles. It blocks receptors at neuromuscular junctions. Why does this lead to paralysis?

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter4: Principles Of Neural And Hormonal Communication
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Problem 4TAHL: Assume presynaptic excitatory neuron A terminates on a postsynaptic cell near the axon hillock and...
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Depression is a condition in which sufferers may feel low mood, lack of motivation and sleep. It is caused by a lack of serotonin in the synaptic cleft of neurone pathways. Serotonin is a neurotransmitter.  

a) Describe how serotonin acts as a neurotransmitter. Using your understanding of synaptic transmission, explain how communication between neurones in serotonin pathways of the brain would be affected in someone with depression.  

b) Doctors use tubocurarine drug as an anaesthetic as it temporarily paralyses muscles. It blocks receptors at neuromuscular junctions. Why does this lead to paralysis?  

 

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