Describe either 1) how you would go about making a goat that produces a silk protein (S) in it's milk or 2) how you could create cattle with the "muscle toughness gene" (M) replaced/knocked-in by a "muscle smoothness" allele from of the same gene from a rabbit. In other words, pick either transgenic or knock-in/out mammal, and tell me how you would make one. Be specific.
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- A survey was conducted in 500 Filipinos belonging to the very low to low income generating familieswith at most a high school diploma. The study found out that 95% of the participants believed thatconsuming GMOs lead to unwanted mutations. Among the most common fear listed was thedevelopment of unwanted phenotypes for their children and grandchildren because of eating GM crops.Based on your knowledge in genetics and on how GMOs are produced, explain why theclaim is impossible to happen. Use one specific example of GMO to justify yourImagine that you caught a female albino mouse inyour kitchen and decided to keep it for a pet. A fewmonths later, while vacationing in Guam, you caughta male albino mouse and decided to take it home forsome interesting genetic experiments. You wonderwhether the two mice are both albino due to mutations in the same gene. What could you do to find outthe answer to this question? Assume that both mutations are recessive.Dr. Frank, Ph.D. says that he is going to use CRISPR-Cas9 to cure a blood disorder that runs in his patient’s family. He says he will use CRISPR-Cas9 to inject the “healthy” allele into the patient’s thigh muscle. Will Dr. Frank's plan work? Why or why not?
- . The human IGF2 gene is autosomal and maternallyimprinted. Copies of the gene received from themother are not expressed, but copies received fromthe father are expressed. You have found two allelesof this gene that encode two different forms of theIGF2 protein distinguishable by gel electrophoresis.One allele encodes a 60K (Kilodalton) blood protein;the other allele encodes a 50K blood protein. In ananalysis of blood proteins from a couple named Billand Joan, you find only the 60K protein in Joan’sblood and only the 50K protein in Bill’s blood. Youthen look at their children: Jill is producing only the50K protein, while Bill Jr. is producing only the 60Kprotein.a. With these data alone, what can you say about theIGF2 genotype of Bill Sr. and Joan?b. Bill Jr. and a woman named Sara have two children, Pat and Tim. Pat produces only the 60K protein and Tim produces only the 50K protein. Withthe accumulated data, what can you now say aboutthe genotypes of Joan and Bill Sr.?The pedigree pictured is of an extended family where a large percentage of family members develop colon cancer at an early age. In this family, individuals either get colon cancer before the age of 16, or they don’t get it at all. a) Based on the information you have been given, what evidence, if any, suggests an inherited contribution to the development of this disease? b) You take a medical history of all 33 people in the pedigree and discover that a large percentage drink a special coffee on a daily basis, while others do not. The individuals who do not drink coffee are I-1, II-2, II-4, II-9, III-7, III-13, IV-1, and IV-3. Could drinking this special coffee play a role in colon cancer? Explain.researchers have been able to clonemammals by fusing a cell having a diploid nucleus (i.e., a somaticcell) with an egg that has had its nucleus removed.A. With regard to maternal effect genes, would the phenotype ofsuch a cloned animal be determined by the animal that donatedthe egg or by the animal that donated the somatic cell? Explain.B. Would the cloned animal inherit extranuclear traits from theanimal that donated the egg or from the animal that donated thesomatic cell? Explain.C. In what ways would you expect this cloned animal to be similarto or different from the animal that donated the somatic cell? Isit fair to call such an animal a clone of the animal that donatedthe diploid nucleus?
- Please explain to me about Mendel monohybrid crosses and the expected ratio of: A) pure cross B) F1 generation C) F2 generation Thank you(p.s. please be detailed in your explaination)A student crossed a female worm homozygous for the dpy-17 e164 allele with a wild-type male worm heterozygous for dpy-17 e164. He then scored all of the developing eggs/larva for the Dpy phenotype. He found 88 with the Dpy phenotype and 98 wild type. Do a Chi square test on phenotypic data to determine if your data supports the hypothesis that the mutation segregates as a single-gene mutation. Show your work in a table and include Null hypothesis Χ2 value dof p value ConclusionIn man, muscular dystrophy is a condition in which the muscles waste away during early life and may result in a shorter life expectancy. It is due to a sex-linked, recessive gene. A certain couple has five children – three boys (ages 1yr, 3yrs, and 10yrs old) and two girls (ages 5yrs and 7yrs old). The oldest boy shows the symptoms of this disease. You are their family physician and they come to you for advice. What would you tell them about the chances of their other children developing the disease?
- 1. Write true if the statement is correct. Right false if the statement is not correct. If the statement is false, then rewrite the statement to make it true. a) Gregor Mendel worked with the fruit fly. b) Blue eyes are an acquired characteristic.To understand this research, you must be familiar with some basic genetic terminology. Drag the terms on the left to the appropriate blanks on the right to complete the sentences. Not all terms will be used. dominant allele phenotype The possession of two different alleles of a particular gene is referred to as Reset Help A variation in a DNA sequence at one particular position is called a heterozygosity genotype recessive allele homozygosity single nucleotide polymorphism The appearance of the organism, its observable traits, are referred to as the A variant of a gene for which an individual must be homozygous in order for it to influence the appearance of the organism is a The set of alleles an organism has for a particular trait is the organism's Submit Request Answera. How would you synthesize a pentaploid?b. How would you synthesize a triploid of genotypeA/a/a?c. You have just obtained a rare recessive mutation a*in a diploid plant, which Mendelian analysis tells you isA/a*. From this plant, how would you synthesize atetraploid (4n) of genotype A/A/a*/a*?d. How would you synthesize a tetraploid of genotypeA/a/a/a?