Basic Clinical Laboratory Techniques 6E
6th Edition
ISBN:9781133893943
Author:ESTRIDGE
Publisher:ESTRIDGE
Chapter2: Basic Hematology
Section2.5: Manual Red Blood Cell And White Blood Cell Counts
Problem 10RQ
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5) Discuss Sickle Cell Anemia.
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Step 1
Humans suffer from a lot of types of genetic disorders. Few of them are common like the sickle-cell anemia, color blindness, and hemophilia, while some are rare like Progeria.
On the basis of the pattern of their inheritance the genetic disorders can be
- autosomal recessive - Two copies of the gene must be mutated for a person to be affected by an autosomal recessive disorder. An affected person usually has unaffected parents who each carry a single copy of the mutated gene and are referred to as carriers
- autosomal dominant - Only one mutated copy of the gene will be necessary for a person to be affected by an autosomal dominant disorder. Each affected person usually has one affected parent
- X-linked dominant and - mutation in X chromosome
- X linked recessive - mutation in X chromosome
For the X-linked disorders males are more susceptible for being infected and affected by the disease.
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