Discuss three types of drug-drug interactions, and explain the links to pharmacodynamics and/or pharmacokinetics, with examples. Give the mechanims.
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Discuss three types of drug-drug interactions, and explain the links to
pharmacodynamics and/or pharmacokinetics, with examples.
Give the mechanims.
Step by step
Solved in 2 steps
- What are the potential implications of genetic variations in drug-metabolizing enzymes on individual response and therapeutic outcomes in clinical pharmacology?Describe the significance of the use of pharmacokinetic parameters in case to calculate appropriate drug dosing regimens.Present the comparison of pharmacokinetics vs pharmacodynamics. Why the identification of different types of receptors is so important for drug’s pharmacodymics?
- Discuss the structures any synthetic drug should initially pass through before acting on the central nervous system Elaborate the physiological processes involved and the necessity of these anatomical structures.What is an example of two drugs that produce a synergistic (also known as hyperadditive) effect? What is the concern about drugs that have synergistic effects? Note: you can describe the classes of drugs rather than using specific drug names.What do you know about pharmacodynamic and pharmacokinetic drug development? Explain briefly
- Based on what you have studied in school, how do you believe the application of pharmacology (the pharmacokinetic and pharmacodynamic principles) optimizes drug development (please cite examples from drug FDA website and/or literature)?What is a synergistic drug interaction? Give ExampleExplain what is meant by a drug’s spectrum and how narrow- andbroad-spectrum drugs differ.