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- Consider the following compound and answer the questions below OH CO2H HO2C Он a) Draw a Fisher Projection for this compound. b) Is this compound chiral or achiral? Explain your answer.2. For each chiral center, prioritize the groups (1-4) attached to each chiral center. Based on your priorities, assign R or S configurations to the chiral center. H H₂CH₂C OH Br H CH3 H L L L H₂C Br H OH CH3 H₂CH₂C H₂CH₂C H₂CH₂CFönt Paragraph Styles 1. Use the lettered molecules below to answer the following questions: CI, H HO H OH H CI HO HO, B D CI ClH H, H CI CI H3CO H E F G A) Identify 1. A pair of enantiomers A 2. A pair of diastereomers D 3. A pair of meso compounds C 4. A pair of identical compounds E and E Differentiate between achiral and meso. Achiral compounds have no chiral centers whereas meso compounds have multiple chiral centers.
- Question 4 of 30 O Macmillan Learning A prochirality center is a precursor to a chirality center. Identify the prochirality centers (if any) in each structure. H3C |||| ··|||| I CI CH H CH3 H == H3C. CH3 -C. CH3 Answer Bank prochirality center4G 08:48 How many chirality centers are present in the compound shown? Cl CI OA1 OB. 3 OC The compound does not have a chirality carbon and therefore is achiral O02 Add a caption... > Status (Custom)1. Consider the following molecules: OH OH A a) Circle the chirality center(s) in each molecule. b) Assign priorities to each chirality center you identified in molecule A and determine if each chirality center is R or S. - c) Determine if each chirality center is R or S for molecule B., d) What is the stereochemical relationship between these two moleu e) Draw the most stable chair form for molecule A. · f) Draw the most stable chair form for molecule B. g) Do you expect one molecule to be more stable than the other? If so, which one and why? If not, why not? " 1 . Convert the following line structure into a Fischer projection. , ОН ОН OH ОН ОН
- Draw (1R,2R)-1-chloro-2-methylcyclopentane. Please draw all four bonds at chiral centers. Use wedge and dash bonds at chiral centers only. Do not use wedges and dashes at non-chiral centers1. Assign priorities to each group on the chirality center in the molecule below (show the priority in the box next to the indicated group). Assign the configuration (R or S) of that chirality center (in the box to the right). 07 OH Configuration:CHEM 431 Programmed Instruction 3 An example of a molecule with two different chiral centers is 2,3-dihydroxybutanoic acid shown below (A) COH He IOH Flying wedge is a two- wedges indicates bonds pr the dashed vertical wedges represent the OH and — H are profecting projecting into the using different colored markers esentation where the solid horizontal and out of the plane of the paper while bonds projecting into the paper. Thus rds you while COOH and-CH3 are OH COOH, and -CH3 by 20. Draw a flying wedge representation of 3 related to A as mirror image. Are A and B superimposable and chiral? What kind of stereomers do they represent? Compounds that contain two different chiral centers can exist as four optically active stereomers 21. Construct the models of the other two stereomers of 213-dihydroxybutanoic acid. The flying
- 1) Circle the chirality centers are in the following compound, Amoxicillin. NH2 H -N. НО OH IZNHCH3 Assign R or S configuration to each chiral center indicated via a (*). HO bH d. CH3 pseudoephedrine List the groups according to decreasing priority as a string of non capitalized letters like abcd. Highest priority 1st. Decreasing priority is : Configuration:Determine whether each molecule shown below is chiral or achiral (not chiral). Br CH3 | HC-C-C -CH3 H2 | H,C-CH H,C CH Cl CI Br Molecule A Molecule B Molecule C O IMG 0391.jpg re to search hp prt