Give a clear handwritten Detailed Solution with explanation needed Shown below is one option for a synthesis that starts with a substrate containing two carbon atoms:ÅThe transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessaryreagents in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correctsolution, provide just one answer.1)AH2) H3O*EPBr3?PCC or DMPB1)2) H3O*Ph3P=CH₂MgHOt-BuOKOH + acidKNa₂Cr₂O7, H₂SO4, H₂ONaOEtDH1) CH3CH₂MgBr;2) H3O+L1) CH 3MgBr;2) H₂O*

Epoxies are open by weak nucleophile.

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Chemistry

Give a clear handwritten Detailed Solution with explanation needed

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter24: Catalytic Carbon-carbon Bond Formation

Section: Chapter Questions

Problem 24.9P

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Question

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Give a clear handwritten Detailed Solution with explanation needed

Shown below is one option for a synthesis that starts with a substrate containing two carbon atoms:
Å
The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary
reagents in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct
solution, provide just one answer.
1)
A
H
2) H3O*
E
PBr3
?
PCC or DMP
B
1)
2) H3O*
Ph3P=CH₂
Mg
HO
t-BuOK
OH + acid
K
Na₂Cr₂O7, H₂SO4, H₂O
NaOEt
D
H
1) CH3CH₂MgBr;
2) H3O+
L
1) CH 3MgBr;
2) H₂O*

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