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H₂C CH₂ NH3 slightly acidic (pH 4-5) 1) LIAIH in diethyl ether 2) H₂O

Introduction to General, Organic and Biochemistry

11th Edition

ISBN:9781285869759

Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Chapter16: Amines

Section: Chapter Questions

Problem 16.17P: 16-17 Propylamine (bp 48°C), ethylmethylamine (bp 37°C), and trimethylamine (bp 3°C) are...

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Concept explainers

Acid Base Titration

An acid-base titration is the method of quantitative analysis for determining the concentration of an acid and base by exactly neutralizing it with a standard solution of base or acid having known concentration.

Question

The following reaction takes place in multiple steps, with a vital intermediate isolated after the treatment with ammonia.

H₂C
CH₂
NH3
slightly acidic (pH 4-5)
1) LIAIH4 in diethyl ether
2) H₂O

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Step 1: Reaction of ketones with ammonia

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Step 2: Reaction of ketone with NH3.

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Step 3: Reduction of imine

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