In glycatysis, conversion of a molecule, of glucose, into 2 Molecules of Pyryvate, results in a net Production of. Molecules of ATP. BJ 3 c) 4 D 6 €) 12
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- Based on your residing of this chapter, what would you expect to be the most immediate effect oil glycolysis, if the steady-state concentration of gJucose-6-P were 8.3 mM instead of 0.083 mM?Energetic of Fructose-1 ,6-bis P Hydrolysis (Integrates with Chapter 3.) The standard free energy change (G) for hydrolysis of fructose-1. 6-bisphosphate (FBP) to fructose-S-phosphate (F-6-P) and P: is -16.7 KJ/mol: FBP + H2O fructose-6-P + Pi The standard free energy change (G) for ATP hydrolysis is -30.5 KJ/mol: ATP + H2O ADP + Pj What is the standard free energy change for the phosphofructokinase reaction: ATP + fructose-6-P ADP + FBP b. What is the equilibrium constant for this reaction? c. Assuming the intracellular concentrations of [ATP] and (ADP] are maintained constant at 4 mM and 1.6 mM, respectively, in a rat liver cell, what will be the ratio of [FBP]/[fructose-6-P] when the phosphofructokinase reaction reaches equilibrium?Handwritten Identify the molecule names, enzyme name, enzyme classification and change in reaction(for glycolysis pathway)
- We have discussed the aerobic metabolism of glucose extensively in this class. To capture and use the energy in glucose to make ATP, we must utilize 4 different sequential pathways/steps. Starting with one glucose molecule and eventually ending with CO, H;O and ATP, list the 4 pathways/steps in order and tell me what molecules enter each pathway, and what the final products of each pathway are. Edit View Insert Format Tools Table 12pt v Paragraph v BIUAv ev Tov : I10) a) Explain why the electron transport chain (ETC) is important for the energy producing in the cellular metabolism. b) Describe and explain the route followed by electrons from glucose to 02 and ATP synthesis. (think the energenics and chemiosmotic theory) Cytnsol mtochondrial montane intarmentne Iligh ner mtochordrial membane Matrt Law (1 ADPP ATPdtermoine numberof ATPS GENERATED FROM COMPLETE oxidation of fructose-6-phosphate isocitrate stearidonic acid [18 carbons triangle 6,9,12,15] indicate where everything comes from ex ATPS FROM GLYCOLYSIS , NADH FROM TCA ETC LIST ALL
- full oxidation of 2 moles of glucose produce 36ATP O 72ATP 48ATP O 106ATP OThis figure depicts the energy investment phase of glycolysis. Enzymes catalyzing the reactions are numbered 1-5. PROCESS: GLYCOLYSIS ATP reac HOCH₂ М OH H Н glucose H Но -O H OH OH 2P Localon ne T 2 NAD P OCH H 6 Но ADP. 2 NADH H OH H + 0 H OH Н 2 POC=0 HCOH I H₂CO P which com Н OH P OCH, 2 ADP H OT О Н НО Но 2 АТР Н H.COH C=O ATP 2011 Pearson Education, Inc This figure depicts the energy payoff phase of glycolysis. Reactions are numbered 6-10. HCOH H₂CO P you isomie 12000 OH POCH₂ H ADP . НО О Н НО H H 2 H₂CO P О О C=O HCO P H₂COH OH (4 POCH, H, OOH CO H c=0 HCOM . H₂CO P О c=0 CO P 11 CH₂ 2 ADP -- 10 nge? 6. Which enzyme (1-10) catalyzes the reaction that gives glycolysis its name? 2 0 0 НИЕ 0=0 CH₂ pyruvate 2 ATP 4. For each glucose molecule catabolized, what are the total or gross products at the end of the glycolysis? 5. What are the NET products of the entire glycolysis pathway from each glucose molecule fully catabolized?ATP ADF R D Match the structure given with the name. Acetyl coenzyme A pyruvate Complex V of the electron transport - oxidative phosphorylation pathway. ATP Synthase Mitochondrion FAD COA not shown D с B A
- CHO CHO CH,OH HO- H Phosphorogluco- isomerase Phosphofructo- kinase Hexokinase но H. но -H- но H- HO- АТР ADP H- HO- -HO- OH H- OH H- OH Via H- -HO- ATP ADP CH2OH CH,OPO,2 ČH,OPO,2 Но nin Glucose A B CH,OPO,2- CH2OPO, Fructose Fo D CH2OH Но H- biphosphate H- HO. HPO,2 / NAD+ / Triose aldolase OH Glyceraldehyde 3- phosphate dehydrogenase phosphate isomerase CH,OPO,2 Via OPO,2 сно HOH E CH,OPO, H- OH LOH CH,OPO, For CH,OPO,2 G COPO,2 он H3C HO. Pyruvic AcidGlycolysis: Kcalmole 0 -18 On the picture above identify all endergonic steps. Glucose Energy levels in glycolysis 10 2 PyruvatesGlycolysis and Krebs cycle pror TWGPalygXphYW9-zKh7Bt-bdNc75nprw176dBUWOA mResponse 23. Select the situation that will NOT happen if ATP synthase is not functioning. O A. Damage to the chemiosmosis process. B. The number of ATP produced is reduced. C. ATP can be produced through oxidative phosphorylation. D. Accumulation of proton ions in the intercellular membrane. 24. Oxidation of organic compounds that produced carbon dioxide, water and release of free energy causing reduction of the final acceptor molecule: oxygen. Justify the reason. ray bonds than those in