In the first step of the TCA cycle the acetyl group of acetyl-CoA is transferred to oxaloacetate to produce citrate. Where will the carbonyl carbon of that acetyl group be after the first CO2 is expelled? Group of answer choices The first carbon of α-ketoglutarate The last carbon of α-ketoglutarate The fourth carbon of α-ketoglutarate The third carbon of α-ketoglutarate
Q: Consider the complete oxidation of one mole of the fatty acyl COA of capric acid (10:0). Determine…
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A: Two answers are correct
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Q: Consider the complete oxidation of one mole of the fatty acyl CoA of myristic acid (14:0). Determine…
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Q: Consider the complete oxidation of one mole of the fatty acyl CoA of capric acid (10:0). Determine…
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Q: When one acetyl CoA is processed through the citric acid cycle, how many times does each of the…
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Q: Consider the complete oxidation of one mole of the fatty acyl CoA of myristic acid (14:0). Determine…
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- Which of the following statements is/are TRUE for the Krebs' cycle? Reaction 1: condensation of acetyl-CoA and oxaloacetate; produces H20. Reaction 3: oxidation of isocitrate to a-ketoglutarate; produces NADH and CO2. Reaction 6: oxidation of succinate to fumarate; produces FADH2 and CO2 Reaction 5: hydrolysis of succinyl-CoA to succinate; produces ATP.To begin the TCA cycle, pyruvate must be converted into acetyl-Coenzyme A (acetyl-CoA) by the enzyme complex of pyruvate dehydrogenase. This complex requires 5 different coenzymes to function properly. What are they?In the pyruvae dehydrogensae complex, acetyl-coa is released by the dihydrolipoyl transacetylase activity. What is the purpose of the following enzymatic activity.
- Identify the Krebs cycle enzyme that consumes a 3-carbon substrate molecule, producing a 2- carbon product molecule (attached to acetyl-CoA), along with NADH, and one molecule of CO2. succinyl CoA synthetase a-ketoglutarate dehydrogenase pyruvate dehydrogenase isocitrate dehydrogenase malate dehydrogenaseFatty acids are activated for breakdown through the action of acyl-CoA synthestase. Which of the following statements regarding acyl-CoA synthetase is not true? ● It catalyzes the addition of CoA to the fatty acid One of the products of the reaction is ADP. O The free energy change for the reaction catalyzed by this reaction is close to 0 kJ/mol, but the subsequent hydrolysis of pyrophosphate drives the reaction forward. O The reaction results in the formation of a thioester bond.Fatty acid biosynthesis begins with the condensation of a two-carbon acetyl residue from acetyl-COA and oxaloacetate, while oxidation leads to the release of two carbon units, acetyl-CoA and fatty acyl-CoA. However, these two processes are not simple reversal. Compare and contrast these two pathways.
- If the carbonyl carbon of acetyl-CoA were marked with 14C, where would that carbon be located within oxaloacetate after one turn of the TCA cycle?Most fatty acids have an even number of carbons and, therefore, are completely metabolized to acetyl-CoA. A fatty acid with an odd number of carbonsis metabolized to acetyl-CoA and one equivalent of propionyl-CoA. The following two reactions convert propionyl-CoA into succinyl-CoA, a citric acidcycle intermediate, so it can be further metabolized. Each of the reactions requires a coenzyme. Identify the coenzyme for each step. From what vitaminsare the coenzymes derived? (Hint: see Chapter 23.) COO− COO−CH2CH2methylmalonyl-CoA succinyl-CoA CH3CH2 SCoAYeasts and plants can use acetyl-CoA as a carbon source by omitting which two steps in the TCA cycle? O Citrate isocitrate; isocitrate → a-ketoglutarate O Isocitrate → a-ketoglutarate; a -ketoglutarate → succinyl-CoA - O Oxaloacetate citrate; malate → oxaloacetate O Succinyl-CoA succinate; succinate → fumarate
- Name one reaction of glycolysis, one anaplerotic reaction, and one reaction of TCA cycle that acetyl-COA allostericqally regulates ( and declare whether it is an activator or inhibitor.)Upon considering the complete oxidation of one mole of fatty acyl (CoA) of an arachidic acid (20:0). Answer the following lettersa. total no. of NADH produced from the oxidation of all acetyl CoA in the acetyl cycleb. total no. of FADH2 produced from the oxidation of all acetyl CoA in the acetyl cyclec. total atp yieldIn order to break the carbon-carbon bond of Acetyl-CoA in a way that does not harm the cell, citrate is produced in the TCA cycle. Explain how switching between 6-carbon, 5-carbon and 4-carbon metabolites eventually allows the two carbons of Acetyl-CoA to be converted to CO2 in a way that does not harm the cell.