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M An obese man was prescibed the lipophilic drug phenobarbital for treatment of seizures. He noticed that it took time before his seisures stopped. What pharmacokinetic parameter increased? How did this affect the time till steady state? ■ A) Clearance; shorter time till steady state B) half-life; longer time till steady state. . C) half-life; shorter time till steady state. ▪ True or False: hepatic enzyme activity is dependent on age. Therefore, concentration of drugs with High EH are affected

M An obese man was prescibed the lipophilic drug phenobarbital for treatment of seizures. He noticed that it took time before his seisures stopped. What pharmacokinetic parameter increased? How did this affect the time till steady state? ■ A) Clearance; shorter time till steady state B) half-life; longer time till steady state. . C) half-life; shorter time till steady state. ▪ True or False: hepatic enzyme activity is dependent on age. Therefore, concentration of drugs with High EH are affected

Basic Clinical Laboratory Techniques 6E
Basic Clinical Laboratory Techniques 6E
6th Edition
ISBN:9781133893943
Author:ESTRIDGE
Publisher:ESTRIDGE
Chapter3: Basic Hemostasis
Section3.6: D-dimers
Problem 1.3CS
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"An obese man was prescibed the lipophilic drug phenobarbital for treatment of seizures. He noticed that it took time before his seisures stopped. What pharmacokinetic parameter increased? How did this affect the time till steady state? B) The patient is noncompliant. A) Clearance; shorter time till steady state ☐ ▪ B) half-life; longer time till steady state. C) half-life; shorter time till steady state. ▪ True or False: hepatic enzyme activity is dependent on age. Therefore, concentration of drugs with High EH are affected A)T B)F Match the drug type with the condition that affects clearance of the drug: A) Low EH drug B) High EH drug 1) Heart failure 2) Liver disease
Transcribed Image Text:"An obese man was prescibed the lipophilic drug phenobarbital for treatment of seizures. He noticed that it took time before his seisures stopped. What pharmacokinetic parameter increased? How did this affect the time till steady state? B) The patient is noncompliant. A) Clearance; shorter time till steady state ☐ ▪ B) half-life; longer time till steady state. C) half-life; shorter time till steady state. ▪ True or False: hepatic enzyme activity is dependent on age. Therefore, concentration of drugs with High EH are affected A)T B)F Match the drug type with the condition that affects clearance of the drug: A) Low EH drug B) High EH drug 1) Heart failure 2) Liver disease
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