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Match the drugs with the corresponding Phase 1 reaction that will happen appropriately with the highligthed portion of the drug. A: C4 of Benzene ring B: Methyl group of Nitrogen C: -NH-NH2 moiety D: N,N-dimethyl moiety E: Ring S CHOICES: A. Desulfuration B. Aromatic hydroxylation C. Hydrazo reduction D. Nitro reduction E. Sulfur oxidation F. Deamination

Match the drugs with the corresponding Phase 1 reaction that will happen appropriately with the highligthed portion of the drug. A: C4 of Benzene ring B: Methyl group of Nitrogen C: -NH-NH2 moiety D: N,N-dimethyl moiety E: Ring S CHOICES: A. Desulfuration B. Aromatic hydroxylation C. Hydrazo reduction D. Nitro reduction E. Sulfur oxidation F. Deamination

Chemistry: Principles and Practice
Chemistry: Principles and Practice
3rd Edition
ISBN:9780534420123
Author:Daniel L. Reger, Scott R. Goode, David W. Ball, Edward Mercer
Publisher:Daniel L. Reger, Scott R. Goode, David W. Ball, Edward Mercer
Chapter20: Chemistry Of Hydrogen, Elements In Group 3a Through 6a, And The Noble Gases
Section: Chapter Questions
Problem 20.10QE
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Match the drugs with the corresponding Phase 1 reaction that will happen appropriately with the highligthed portion of the drug.

 

A: C4 of Benzene ring

B: Methyl group of Nitrogen

C: -NH-NH2 moiety 

D: N,N-dimethyl moiety

E: Ring S
 

CHOICES:
A.

Desulfuration
B.

Aromatic hydroxylation
C.

Hydrazo reduction
D.

Nitro reduction
E.

Sulfur oxidation
F.

Deamination
G.

N-demethylation
A CI CI ZI CI B\ „N ZI N- N O ZI ·S O CL O ANNH, N 2-3/2 N NH NH₂ D N ZI N S H E S `N N
Transcribed Image Text:A CI CI ZI CI B\ „N ZI N- N O ZI ·S O CL O ANNH, N 2-3/2 N NH NH₂ D N ZI N S H E S `N N
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