Poliovirus contains a protein that possesses an NLS. A drug is developed that binds and hides this sequence on the viral protein. What happens to this viral protein, in the presence of the drug? Select all that are true. O a. The viral protein is secreted Ob. The viral protein is found in the endomembrane system OC. The viral protein is found in the ER Od. The viral protein is now found in the cytoplasm O e. The viral protein can now enter the nucleus
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- Poliovirus contains a protein that possesses an NLS. A drug is developed that binds and hides this sequence on the viral protein. What happens to this viral protein, in the presence of the drug? Select all that are true. a. The viral protein is now found in the cytoplasm O b. The viral protein is found in the endomembrane system Oc. The viral protein is secreted O d. The viral protein is found in the ER O e. The viral protein can now enter the nucleusDuring viral infection, attachment is usually specific to a particular celltype becausea. the virus is attracted to the appropriate host cells by proteinssecreted into the extracellular fluid.b. the virus recognizes and binds to specific molecules in thecytoplasm of the host cell.c. the virus recognizes and binds to specific molecules on the surfaceof the host cell.d. the host cell produces channel proteins that provide passageways forviruses to enter the cytoplasm.e. the virus releases specific proteins that make holes in the membranelarge enough for the virus to enter.The Influenza virus is a (-)ss RNA virus that _________ bring its own RNA Polymerase into the host cell with it. This virus will gain entry into host cells through _____________ by using the Hemagglutinin Spike protein present on its envelope, which allows the viral envelope to merge with the host cell membrane. Select one: a.Does not need to / Fusion b.None of the Above c.Needs to / Membrane Fusion d.Does not need to / Endocytosis e.Needs to / Endocytosis
- The Adaptive Immune Response Is a Specific Defense Against Infection Researchers have been having a difficult time developing a vaccine against a certain pathogenic virus as a result of the lack of a weakened strain. They turn to you because of your wide knowledge of recombinant DNA technology and the immune system. How could you vaccinate someone against the virus, using a cloned gene from the virus that encodes a cell-surface protein?You are studying a new retrovirus. The viral protein (X) appears to play a role in the export of the viral genomes to the cytoplasm. Protein X brings viral DNA to the cytoplasm and returns back to the nucleus after genome export is complete. Researchers have developed a new drug for the virus. Following treatment with the new drug, the viral protein stays in the nucleus and cannot export the viral genomes. What is the most plausible and logical function of the drug? Use your knowledge of nuclear transport to answer this question. O A. The drug inhibits the binding of the viral protein and the viral genomes to the import receptor. B. The drug inhibits the binding of Ran-GTP to the nuclear export receptor in nucleus. C. The drug promotes the Ran GAP activity. D. The drug blocks the NLS on the viral protein.A viral mutation that causes changes in the glycoprotein spikes would affect which aspect of the virus? The virus would become lysogenic and incorporate its genome into the host cell genome. The virus would enter the host by a combination of endocytosis and fusion. The virus would lose its viral envelope and become a naked virus. The virus would adsorb to different host cells and its host range would be altered. The viral genome would not require uncoating once inside the host cell.
- A viral mutation that causes changes in the glycoprotein spikes would affect which aspect of the virus? The virus would become lysogenic and incorporate its genome into the host cell genome. The virus would enter the host by a combination of endocytosis and fusion. The virus would lose its viral envelope and become a naked virus. The virus would attach to different host cells and its host range would be altered. The viral genome would not require uncoating once inside the host cell.Find the wrong information about virus attachment and absorption to host cell. A. The surface capsid proteins of naked viruses bind to a specific cell receptor on host cell. B. For enveloped viruses, the spikes are responsible for binding to a specific cell receptor. C. A cell lacking a receptor for a specific virus is not infected by that virus. D. Animal viruses, such as HIV are highly specific and they can only infect particular cell types. E. All of these are true.Which of the following statements about ribosomes is correct? * a. the number of ribosomes in a cell seldom exceeds 50 b. the active site of a ribosome contains mostly protein molecules c. structurally, ribosomes have two rRNA- protein subinuts d. no correct response What is the complementary hnRNA base sequence produced from the DNA base sequence 5' C-T-A-T-A-C 3' ? * a. 3' C-T-A-G-A-T 5' b. 3' C-G-G-A-T-A 5' c. 3' G-A-U-A-U-G 5' d. 3' G-A-T-A-T-G 5' The product of the first phase in protein synthesis is * a. DNA molecules b. RNA molecules c. both RNA and DNA molecules d. neither RNA and DNA molecules
- If the HIV did not have a reverse transcriptase enzyme, then which of the following would apply? Select one: a. The virus can make use of the reverse transcriptase enzyme from the host cell to convert its RNA into DNA b. Viral particles will be produced without reverse transcriptase enzyme since the original HIV is an RNA virus and needs to assemble RNA ant coat proteins together c. The virus will manufacture its proteins from its RNA using translation and ribosomes from host cell d. Provirus will not be formed and assembly of viral particles will never occur e. The virus will not be able to recognise the host cell and therefore entry into the cell is blockedThe spike proteins of a coronavirus are one half of the Velcro mentioned in the video, and the other half of the Velcro consists of molecules on the surface of human cells. What happens after coronavirus spike proteins bind to molecules on the surface of a human cell?Researchers studying the SARS-CoV-2 virus, also known as COVID-19, have found that the virus is able to circumvent its host cell's normal defenses by leaving the cell via its lyso- somes rather than its normal secretory vesicles, as illustrated in the figure below. endoplasmic reticulum nucleus disrupted lysosomal functions Entry and egress of the SARS-CoV-2 virus A Golgi complex Which of the following best explains their findings? B lysosome (deacidified) С lysosome (acidified) B-coronavirus normal biosynthetic pathway egress via lysosomal trafficking SARS-CoV-2 inhibits lysosomes of its host cells by decreasing the pH within them. SARS-CoV-2 activates lysosomes of its host cells by decreasing the pH within them. SARS-CoV-2 activates lysosomes of its host cells by increasing the pH within them. D SARS-CoV-2 inhibits lysosomes of its host cells by increasing the pH within them.