Please don't provide handwritten solution .... Predict the intermediate 1 and final product 2 of this organic reaction:علامہCN +HNaOMeH*12work upYou can draw 1 and 2 in any arrangement you like.Note: if either 1 or 2 consists of a pair of enantiomers, just draw one structure using line bonds instead of 3D (dash and wedge) bonds at the chiral center.

reaction between an aldehyde and a cyanide inthe presence of sodium methoxide produces an alcohol…

Answered: Predict the intermediate 1 and final…

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter13: Substitution

Section: Chapter Questions

Problem 2E

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2. What is the effect of a tert-butyl group when placed in a 6 membered ring? I've been told it "locks" the conformation but I don't understand what that means exactly. Does it have an effect on reactivity? Does it just mean the ring cannot undergo a ring flip? For example, in the reaction below would the ketone reduce to an alcohol as normal, as though the tBu group LIAIH4 *tBu wasn't there?
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Alcohols undergo an oxidation reaction to yield carbonyl compounds on treatment with CrO3. For example, 2-tert-butylcyclohexanol gives 2-tert-butylcyclohexanone. If axial OH groups are generally more reactive than their equatorial isomers, which do you think reacts faster, the cis isomer of 2-tert-butylcyclohexanol or the trans isomer? Explain.

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