Question 8 of 26 Suppose a drug molecule binds to a protein target. Complete the table which describes possible noncovalent intera NCI) in the binding site. Assume the drug has a variety of types of polar and nonpolar regions. Type of NCI ionic interaction Species able to form that NCI any species with permanent dipoles (C=O, etc.) H bonded to N, O, or F and a lone pair on N, O, or F Answer Bank Parameters affecting the NCI strength and orientation of dipole orientation polarizability, size: molecular weight

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
icon
Related questions
icon
Concept explainers
Question
Question 8 of 26
Suppose a drug molecule binds to a protein target. Complete the table which describes possible noncovalent interactio
(NCI) in the binding site. Assume the drug has a variety of types of polar and nonpolar regions.
Type of NCI
ionic interaction
dipole-dipole
Species able to form that NCI
any
species with permanent
dipoles (C=O, etc.)
H bonded to N, O, or F and
a lone pair on N.O.or F
Answer Bank
dielectric size; type of charge
ions; charged species
hp
dispersion
Parameters affecting the NCI
hydrogen bond
strength and orientation
of dipole
orientation
polarizability; size; molecular weight
Transcribed Image Text:Question 8 of 26 Suppose a drug molecule binds to a protein target. Complete the table which describes possible noncovalent interactio (NCI) in the binding site. Assume the drug has a variety of types of polar and nonpolar regions. Type of NCI ionic interaction dipole-dipole Species able to form that NCI any species with permanent dipoles (C=O, etc.) H bonded to N, O, or F and a lone pair on N.O.or F Answer Bank dielectric size; type of charge ions; charged species hp dispersion Parameters affecting the NCI hydrogen bond strength and orientation of dipole orientation polarizability; size; molecular weight
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 3 steps

Blurred answer
Knowledge Booster
Proteins
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education