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- Rank thr stability of the following sets of reaction intermediates.Consider the taollowing transtormation to answer the 3-part question. "Br OH CI 2 i) Can substrate 1 undergo intramolecular SN2 reaction? | Select] ii) Can substrate 2 undergo intramolecular SN2 reaction? [ Select ] iii) Can substrate 3 undergo intramolecular SN2 reaction? ( Select )Draw the mechanism of the following alkylation reaction that occurs via an enolate intermediate. о сн, о сн, (1) LDA Ph-C-CH-CH, Ph-C-C-CH, (2) Ph — CH, — Вr ČH,-Ph
- Here is the same figure as in the previous two questions, but omitting the red circles. Cys157 Cys157 Cys157 His296 His296 His296 LOH HN HN HN N? -CO2 CH2 Asn329 Asn329 Asn329- Cys157 His296 LOH HN H HyC. Asn329 Which of the following roles is played by the imidazole side chain of His296? Pick the one best [ Select ] answer.In the following reaction, iodine monochloride (ICI) effectively serves as a source of an electrophilic lodonium species, l'U. Org. Chem 2005, 70, 3511-3517). Propose a mechanism for the formation of each of the two products, A and B. OMe Fr A MeO ICI OMe BExpain the mechanism of given reaction
- A) Describe substrate structure and condition that favor SN1 reactions taking place over SN2. B) What conditions promote E2 reactions.Identify A and B in the following reaction sequence. Label each process asconrotatory or disrotatory.Please draw PLP-dependent mechanisms for this reaction. General acids/bases may be involved as needed