Answered: Show how to synthesize the following…

Show how to synthesize the following amines from the indicated starting materials byreductive amination. ) N-benzylpiperidine from piperidine

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter24: Amines And Heterocycles

Section24.SE: Something Extra

Problem 37MP

See similar textbooks

Related questions

Q: a) Show the mechanism of synthesis of an amide from an ester and a primary amine: b) The ester…

Q: b)Congo Red indicator is synthesized via coupling reaction of diazonium salt which is obtained by…

A: The structures of the required reactants are

Q: Which of the following methods could be used to synthesize propylamine? 1. Gabriel amine synthesis…

A: Propyl amine can be prepared by using all the four methods given in question.

Q: Show how to prepare the following aromatic amines by aromatic nitration, followed by reduction. You…

A: Preparation of c) m-bromoaniline : Benzene is taken as the starting material. The correct sequence…

Q: Show how you would accomplish the following syntheses using amides as intermediates.You may use any…

A: The structure of benzoic acid is shown below: The structure of benzyldimethylamine is:

Q: Give the products expected when the following tertiary amines are treated with a peroxyacid and…

A: The structure of N,N-diethylhexan-2-amine is,

Q: Explain why a secondary amine forms a nitrosamine rather than a diazonium salt when it reacts with…

Q: Which of the following primary amines cannot be made by the given synthetic sequences? R's can be…

A: First reaction involves, step1 is imine formation and step 2 reduction of imine to amine. Second…

Q: Show how Gabriel syntheses are used to prepare the following amines.(a) benzylamine

Q: Show how to synthesize the following amines from the indicated starting materials…

A: Given The given organic compounds are N-butylpiperidine and piperidine.

Q: - How might the following amine be prepared using reductive amination reactions? Show all precursors…

Q: Each pair of compounds below can be separatedusing acid/base extraction. Provide the common acid or…

A: Answer -

Q: NH₂ The following reaction will give 3 different organic products. Sketch the three products. CH3Br…

A: The Gabriel synthesis is a chemical reaction that transforms primary alkyl halides into primary…

Q: The two most general amine syntheses are the reductive amination of carbonyl compounds and the…

A: Amines are the compounds that have NH2 group present in it. The lone pair of nitrogen can be donated…

Q: Show how you would use bromination followed by amination to synthesize the followingamino acids.(a)…

A: Hell–Volhard–Zelinsky reaction: Alpha-bromination of aliphatic carboxylic acids in the presence of…

Q: Show how phenylalanine can be prepared by reductive amination of an α-ketocarboxylic acid.

A: An organic group in which carboxylic group and ketone group are present is called ketocarboxylic…

Q: Show how to synthesize the following amines from the indicated starting materials…

A: INTRODUCTION: Acylation is defined as the addition of acyl group to a compound.The compound which…

Q: Show how to synthesize the following amines from the indicated starting materials.(a)…

A: Given reactions, (a) N-cyclopentylaniline from aniline (b) N-ethylpyrrolidine from pyrrolidine

Q: The synthesis of the following compound involves the use of an epoxide. Describe the retrosynthetic…

A: Under acidic condition ring opening of epoxide occurs from the more hindered site.

Q: Based on this retrosynthetic analysis, propose a synthesis of the anticoagulant (a substance that…

A: Diphenadione can be produced from the retrosynthetic reaction of diethyl pthalate and the given…

Q: Following is a series of anorexics (appetite suppressants). As you study their structures, you will…

A: Clobenzorex is a compound is a type of a drug which used to suppress a person appetite, this drug is…

Q: Which of the following statements is correct? An aldehyde can react with a secondary amine through a…

Q: Prozac may be prepared via a Mannich reaction using which amine? Benzylamine Methylamine Ethylamine…

A: A chemical reaction in which organic compounds take part is called organic reactions. Organic…

Q: DIN a secondary amine gives a diazonium salt upon reaction with HNO₂, HCI at 0°C can undergo…

Q: Show how you would prepare the following amide starting with bromocyclohexene and any other…

Q: Excess ammonia must be used when a primary amine is synthesized by reductive amination. What product…

A: Synthesis of primary amine by reductive elimination takes place as follows:

Q: Show how to synthesize the following amines from the indicated starting materials byreductive…

A: To synthesize N-Cyclohexylaniline from cyclohexanone The primary amine can be synthesized from the…

Q: Reduction of aromatic nitro-compounds using Sn and HCl gives :Select one a. aromatic secondary…

A: Given, Reduction of aromatic nitro compounds using Sn and HCl gives = ? Sn/HCl - is a reducing agent…

Q: Show how to synthesize the following amines from the indicated starting materials.(a)…

A: Amines are the compounds that have NH2 group present in it. The lone pair of nitrogen can be donated…

Q: Show how to synthesize the following amines from the indicated starting materials byreductive…

A: Amines are the organic molecule contains one or more nitrogen atom. Reductive amination is the…

Q: Show how to synthesize the following amines from the indicated starting materials byreductive…

A: Concept introduction: The reaction of a primary amine with either aldehydes or ketones in the…

Q: Following are structural formulas for two more widely used sulfonylurea hypoglycemic agents.Show how…

A: To synthesize Gliclazide, diethyl carbonate can be treated with the hydrazine to make the carbamic…

Q: Please complete the following synthesis. via reductive amination; provide two methods. each method…

Q: Show how Gabriel syntheses are used to prepare the following amines. g@aminobutyric acid

A: Gabriel syntheses: Alkyl halide is treated with phthalimide in the resence of base to give N-alkyl…

Q: Show how to prepare the following aromatic amines by aromatic nitration, followed by reduction. You…

A: The structure of p-bromoaniline is shown below.

Q: Show how you can synthesize the following tertiary amine three different ways, each using a…

A: SOLUTION: Step 1: The different methods in which a tertiary amine can be synthesized using a…

Q: Show how to prepare the following aromatic amines by aromatic nitration, followed by reduction. You…

A: Nitration is chemical process in which nitro group is introduced into an organic compound.

Q: the scheme shown consists of key steps in the acidic hydrolysis of an amide. Complete the mechanism…

Q: The following product can be made from the reductive amination of which combination of compounds?…

Q: a) What are the difficulties with the following reaction to synthesize an amine. + HBr Br + NH NH2…

A: Given reaction is :

Q: Which of the following reaction or reagent does not produce an amine molecule? A. Curtius…

A: The given reactions are A. Curtius rearrangement B. Reaction of oximes with metallic sodium in…

Q: Reaction of a primary or secondary amine with diethyl carbonate under controlled con- ditions gives…

A: The mechanism for a given reaction has to be given.

Question

Show how to synthesize the following amines from the indicated starting materials by
reductive amination.
) N-benzylpiperidine from piperidine

Definition Definition Organic compounds with a nitrogen atom having a lone pair of electrons on it. Amines are derived from ammonia (NH 3 ), wherein hydrogen atoms are substituted by an aryl or alkyl group.

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Trending now

This is a popular solution!

Step by step

Solved in 2 steps with 3 images

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

Show how to synthesize the following amines from the indicated starting materials byreductive amination. cyclohexylamine from cyclohexanone
Show how to synthesize the following amines from the indicated starting materials byacylation–reduction. b) N-benzylaniline from aniline
Show how to synthesize the following amines from the indicated starting materials byreductive amination. ) N-cyclohexylaniline from cyclohexanone
Indicate whether the following statement is true or false. Aliphatic amines are more basic than ammonia, whereas aromatic amines are less basic than ammonia. When amines are reacted with bases, they form ammonium salts. Benzenesulfonyl chloride or p-toluenesulfonylchloride give N-substituted sulfonamides with primary and secondary amines. Derivative of primary amines is insoluble in dilute NaOH
Show how to prepare the following aromatic amines by aromatic nitration, followed by reduction. You may use benzene andtoluene as your aromatic starting materials. c) m-bromoaniline
Show how to synthesize the following amines from the indicated starting materials.(a) N-cyclopentylaniline from aniline
What carboxylic acid and amine are needed to synthesize the pain reliever phenacetin? Phenacetin was once a component of the over-the-counter pain reliever APC (aspirin, phenacetin, caffeine), but it is no longer used because of its kidney toxicity.
Which combination of carbonyl compound and amine can be used to prepare the following product by reductive amination?
Provide the steps to convert the following aldehyde to the given amine product.
Show how to synthesize the following amines from the indicated starting materials byreductive amination.(a) benzylmethylamine from benzaldehyde
Show how to synthesize the following amines from the indicated starting materials.(a) N-cyclopentylaniline from aniline (b) N-ethylpyrrolidine from pyrrolidine
a) What are the difficulties with the following reaction to synthesize an amine. + HBr Br + NH3 NH2 b) Show a possible alternatives to this synthesis.