SN2 Reaction lodide ion is an effective nucleophile in S2 displacements. In acetone solution, other alkyl halides can be converted to alkyl iodides: CH;CH2 CH,CH3 I-C H;C H acetone X- Na I- H CH; Na X X Clor Br TR) Although you might expect such a reaction to be reversible, it can be made to proceed in the forward direction by using anhydrous acetone as the solvent because sodium iodide is soluble in this solvent, but sodium chloride and sodium bromide are not. We can detect whether a reaction has occurred by the formation of a precipitate of sodium chloride or bromide.

SN2 Reaction lodide ion is an effective nucleophile in S2 displacements. In acetone solution, other alkyl halides can be converted to alkyl iodides: CH;CH2 CH,CH3 I-C H;C H acetone X- Na I- H CH; Na X X Clor Br TR) Although you might expect such a reaction to be reversible, it can be made to proceed in the forward direction by using anhydrous acetone as the solvent because sodium iodide is soluble in this solvent, but sodium chloride and sodium bromide are not. We can detect whether a reaction has occurred by the formation of a precipitate of sodium chloride or bromide.

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter16: Chemistry Of Benzene: Electrophilic Aromatic Substitution

Section16.SE: Something Extra

Problem 30MP: The carbocation electrophile in a Friede1-Crafts reaction can be generated by an alternate means...

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