The cell in the center of the electron micrograph above is important in wound healing and plays a role in the pathological process underlying Dupuytren's contracture. Which of the following cell types is depicted? A. Endothelial cell B. Myoepithelial cell C. Myofibroblast D. Pericyte E. Smooth muscle cell
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- In order to ensure good collagenization, which of the following is true during the proliferation stage of tissue repair? OTwo of the answers are correct A great deal of oxygen is required for fibroblast energy source and as building blocks of collagen O All of the answers are correct O The collagen is initially laid down randomly in the wound, not necessarily along the lines of force the tissue will experience. O Most collagenization occurs by 4-6 days after injuryt was seconds ago BIUA = 三 + E I 1 1 II I 2 1111 11 1111II14 1111 III5 III 1 16 Which of the following is not accurate concerning regeneration following tissue injury? The epithelium will thicken. The normal function of the damaged tissue will be restored. The scab will detach as the epithelium thickens. The normal function of the damaged tissue will not be restored. MacBook Pro !! II lıli 日In the image above, the elongated dark (heterochromatic) nuclei represent A Satellite cells B Fibroblasts in the perimysium Fibroblasts in the endomysium Muscle fibers E Fibroblasts in the epimysium F) Endothelial cells
- How are fibroblasts organised In loose fibrous tissue? Answers A -E A Clustered in groups derived by the same progenitor, ie. isogenic groups Ordered at the edge of bone lamellae with long cellular extensions that enable cell-cell communication c Organised parallel between the collagen fibres D Scattered throughout the tissue without a particular pattern E They form epithelial like-layers around the bonegive a under microscophe slides a histological appearance of a cell on its normal, reversible and irreversible injury stateCan you match the sacromere anatomy with the proper answer from the list below the table graph? Sarcomere Anatomy Description/Reaction Thin Filaments ? Thick Filaments ? A Band ? I Band ? M Line ? H Zone ? Z Disc ? A) G-Actin, F-Actin, Troponin, Tropomyosin B) Myosin C) Bisected by the M Line, this area shows only the thick filaments without any thin filamentous overlap D) The point of origin for myosin filaments found in the center of the sarcomere E) An area in the center of the sarcomere marked by the entire length of the thick filaments F) A space between sarcomeres with the z-disc in the center; this region shows Actin's anchorage points and extension without myosin overlap G) Anchoring point for the thin filaments
- A muscle biopsy is taken after 12 days of heavy strength training. The muscle cells appear to have a greater cross- sectional area than before the training. What is the best conclusion? After 12 days of heavy strength training, muscle cells show hypertrophy. Muscle cells undergo hyperplasia after 12 days of strength training. Strength training does not cause any increase in muscle cell volume. Hyperplasia does not occur in muscle cells with heavy strength training.Define the following terms:a. microfilamentb. F-actinc. G-actind. ameboid movemente. intermediate filamentf. keratinDistinguish between regeneration and fibrosis. Which process restores normal cellular function? What good is theother process if it does not restore function?
- What is the role of cells in tissue engineering in general (why do we use cells in tissue engineering)? Describe what we see in the Figure below, what do the colours indicate/what could they stain for? Red Blue GreenWhich of the following statements can CORRECTLY be made about muscle tissue? 1. The main characteristic of muscle tissue is its ability to contract, or shortens, making movement possible. II. Skeletal muscle fibers appear banded with many cells at the periphery and under involuntary control. II. Cardiac muscle cells are cylindrical, not striated, and have a centrally located nucleus and under involuntary IV. Smooth muscle cells are tapered at each end, are not striated, and have a single control. nucleus and under involuntary control. O Statements I and IV are correct O Statements 1, II, IV are correct O Statements i, II, III, and V are correct O Statements Il and Itl are correct 21 22 23 24 25 26 27 28 29 30Imagine that you are designing a scaffold for cartilage tissue engineering? Describe the requirements of engineered scaffolds for cartilage tissue engineering application. How would you manufacture that desired scaffold? Briefly explain manufacturing method.