The enzyme useful in the treatment of leukemia is which of the following? a. alpha-chymotrypsin b. Asparaginase c. Streptokinase d. Hyaluronidase
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- A70-year-old woman with a long history of systemic lupus erythematosus has been receiving prednisone for the past 3 months. She also has been receiving captopril to treat her hypertension. Which of the following laboratory results would be evident in this patient? ???? ?????? ?? ????? ?? ???? ???????? a. Hyperglycemia b. Hyponatremia c. Hypercalcemia d. Hypocholesterolemia e. HypokalemiaLactic acidosis is a potential adverse side effect most commonly seen with which of these agents? Select one: a. Metformin (Glucophage) b. Glipizide (Glucotrel c. Repaglinide (Prandin) d. Miglitol (Glyset).In acute lymphoblastic leukemia, the cancerous white blood cells typically lack the enzyme asparagine synthetase. Why is the administration of asparaginase an eff ective therapy for this type of cancer?
- Which of the following medications is associated with cumulative doses resulting in delayed myelotoxicity? a. Carmustine b. Ifosfamide c. Methotrexate d. Oxaliplatinplease help me I can't find answers for these questions: here is the link for the article https://www.pbs.org/wgbh/nova/transcripts/2805cancer.html What type of substances are angiostatin and endostatin and where are they produced? What do they do? A) describe the experiments using cow bones to discover anti-angiogenic substances. Why was this used as a source of these potential proteins? B) describe the “accidental” discovery of a novel antiangiogenic substance because of lab contamination?Vancomycin is a very potent antibiotic use for several diseases such as infective endocarditis, septicemia and various skin and soft tissue infections. Which of the following statements is NOT TRUE regarding vancomycin A. Inhibit cell wall synthesis by binding to the PBP B. Dosage must be increased in patients with end-stage renal disease C. Glycoprotein antibiotic D. Best absorbed when taken orally E. Bacteriostatic F. First line of treatment for MRSA
- Kelly has breast cancer. Her doctors determined her breast cancer wasaggressive, which meant that she needed to undergo chemotherapy. Her doctors recommended a combination of docetaxel (Taxotere®), carboplatin, and trastuzumab (Herceptin®). The following is her blog entry after her second chemo treatment: As far as chemo symptoms go, the biggest has been fatigue. I was just tired, grumpy, and not my usual, peppy self most of the week. Other very minor things—tiny bit of stomach upset at the beginning of the week, but just enough to make me not feel like eating a big steak, not enough to keep me from eating soup or sandwiches. My scalp felt a little irritated—for the girls out there, itwas the feeling of having my hair in a tight ponytail all day and then letting it down, and the follicles just feel prickly—this is normal for several daysbefore the hair falls out. Also, I have a weird dry mouth feeling, so some things taste a little different. But seriously, these are really minor…For each of the following examples, indicate whether the drug is acting on physical process, chemical process or enzymatic system (your answer should be only; Physical, Chemical or Enzymatic). A. A drug is used as an antidote in lead poisoning and acts by binding to lead particles in body (chelation therapy). B. A drug acts to reduce flatulence and acts by reducing the surface tension of intestinal gas bubbles in the GI tract (e.g. Simethicone). C. A drug competes with alpha-glucosidase in intestine to reduce glucose conversion from disaccharides (e.g. Acarbose).Which of the following sentences is CORRECT? A. P53 is an example of tumour activator gene B. leukotrienes are derived from arachidonic acid by cyclooxygenase C. effective bacteriocidal enzymes are contained in lysosome of the lymphocytes D. Gram stain is the most commonly used tissue stain for routine histological examination E. proteoglycans are located in ground substance of the ECM in connective tissues and basement membrane
- ABC is an oral medicine and is a co-formulation containing Drug X and Drug Z. When administered alone, Drug X which is the active ingredient, exhibits poor bioavailability. Drug X is known to be metabolised by hepatic CYP enzymes. Studies have shown that addition of Drug Z results in higher blood levels of Drug X. 1) How this might be possible ? 2) Predict possible changes to the pharmacokinetic parameters of Drug X when co-administered with Drug Z ? 3) Clinical outcomes brought about by using this co-formulation ABC ?The terminal sugars of the antigenic determinants of A and B blood groups are: O a. N-acetyl-galactosamine and N-acetyl glucosamine O b. D-galactose and N-acetyl glucosamine O c. N-acetyl-D-glucosamine and L-fucose O d. N-acetyl-galactosamine and D-galactoseMia has been diagnosed with tuberculosis. Her skin test for PPD is positive. Which of the following would be the drug of choice for Mia? Multiple Choice Rifadin Myambutol INH Pyrazinamide