The pka of phenol (C6H5OH) is 10.0. When a nitro group (NO2) is attached to the ring, the pK, decreases, as shown for the ortho, meta, and para isomers. OH OH ОН OH NO2 (a) Explain why the pK, values of all three isomers are lower than the pka of phenol itself. (b) Explain why the meta isomer has the highest pka of `NO2 Phenol NO2 the three isomers. pKa = 10.0 7.23 8.35 7.14

The pka of phenol (C6H5OH) is 10.0. When a nitro group (NO2) is attached to the ring, the pK, decreases, as shown for the ortho, meta, and para isomers. OH OH ОН OH NO2 (a) Explain why the pK, values of all three isomers are lower than the pka of phenol itself. (b) Explain why the meta isomer has the highest pka of `NO2 Phenol NO2 the three isomers. pKa = 10.0 7.23 8.35 7.14

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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The pk, of phenol (C,H5OH) is 10.0. When a methyl (CH3) group is attached to the ring, the pK, increases, as shown here for the ortho, meta, and para isomers. OH ОН ОН ОН CH3 (a) Explain why the pk, values of all three isomers are higher than the pk, of phenol itself. (b) Explain why the meta isomer has the lowest pk, of CH3 Phenol CH3 the three isomers. pKa = 10.0 10.3 10.1 10.2
A) Phenol Red is a weakly acidic dye which is yellow in the HA form and red in the A form. What concentration of Phenol Red is required to obtain an absorbance of 0.50 at 550 nm at pH 7.8? Note: ε550 of A = 2.5 x 104 M-1 cm-1; ε550 of HA = 0; pKa = 7.8. B) What would the absorbance of the solution in part (a) be if the pH was 8.8?
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(a) Tsomane and Nyiko were given a task of synthesising methylenecyclohexane 2. After a brief discussion with each other, Tsomane proposed Method A to synthesise 2 from cyclohexanone 1 while Nyiko proposed Method B that started from hydroxymethylcyclohexane 3. Each student believed that their proposed method is better than the other. (Scheme below) (1) Ph Ph 836 Ph THF A 1 B H₂SO4 100 °C 3 OH Which of the two methods (A or B) is more likely give high yield of methylenecyclohexane 2? Briefly explain.
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