The start drug is Tolbutamide and the product is Chlorpropamide. Which of the following is incorrect? a. the -CH3 groyp is replaced with Cl atom to prevent oxidation of –CH3 group b. The -CH3 group in Tolbutamidw can be easily oxidized into -CH20H, and then to –CO2H c. this modification is used to prolong the duration of action of chlorpropamide d. this modification is achieved by an oxygen enzyme e. none of the above
The start drug is Tolbutamide and the product is Chlorpropamide. Which of the following is incorrect? a. the -CH3 groyp is replaced with Cl atom to prevent oxidation of –CH3 group b. The -CH3 group in Tolbutamidw can be easily oxidized into -CH20H, and then to –CO2H c. this modification is used to prolong the duration of action of chlorpropamide d. this modification is achieved by an oxygen enzyme e. none of the above
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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The start drug is Tolbutamide and the product is Chlorpropamide. Which of the following is incorrect?
a. the -CH3 groyp is replaced with Cl atom to prevent oxidation of –CH3 group
b. The -CH3 group in Tolbutamidw can be easily oxidized into -CH20H, and then to –CO2H
c. this modification is used to prolong the duration of action of chlorpropamide
d. this modification is achieved by an oxygen enzyme
e. none of the above
Transcribed Image Text:H₂C-
00
-S
HN-
tolbutamide
NH(CH2)3CH3
CI-
0 0
HN-
chlorpropamide
NH(CH2)CH3
O
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