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- Considering the following chromosome which is represented as a series of genes on each arm separated by the centromere. Describe the type of mutation required to produce each of the mutant chromosomes below. ABCDEFG*HIJKLMNAssuming sexual reproduction and that no mutations have occurred. Please draw one possible genotype for offspring of these parents including two chromosomes with 3 alleles each.which are major mechanisms by whichchromosomal rearrangements take place
- Equalizing the Expression of X Chromosome Genes in Males and Females Individuals with an XXY genotype are sterile males. If one X is inactivated early in embryogenesis, the genotype of the individual effectively becomes XY. Why will this individual not develop as a normal male?What may be expected to happen chromosomally and genetically to: a chromosomes that contains two centromeres.Nondisjunction which can affect sex chromosomes as well as autosomal chromosomes as a common cause of genetic disorders. Use the space provided to illustrate the process of nondisjunction with the end result being that one cell exhibits in the monopsony me while other one exhibits trisomy. Hint: a sperm will fertilize the egg and add it’s chromosome in the last step)
- A female patient 19 years old, whose symptoms areanemia and internal bleeding due to a massive buildupof leukemic white blood cells, is diagnosed withchronic myelogenous leukemia (CML). Karyotypeanalysis shows that the leukemic cells of this patientare heterozygous for a reciprocal translocation involving chromosomes 9 and 22. However, none of thenormal, nonleukemic cells of this patient contain thetranslocation. Which of the following statements istrue and which is false?a. The translocation results in the inactivation (loss offunction) of a tumor-suppressor gene.b. The translocation results in the inactivation (loss offunction) of an oncogene.c. There is a 50% chance that any child of this patientwill have CML.d. This patient is a somatic mosaic in terms of thekaryotype.e. DNA extracted from leukemic cells of this patient,if taken up by normal mouse tissue culture cells,could potentially transform the mouse cells intocells capable of causing tumors.f. The normal function of the…Meiosis Card Sort- Write the letter for each stage in the correct orderAdentify the type of chromosomal abnormality shown here: inversion O deletion O insertion O translocation. 1 Previous
- Why is karyotyping significant in understanding chromosomal abnormalities? Short essay only thanks please the main answerA reciprocal translocation between chromosomes9 and __ contributes to chronic myelogenous leukemia.Continuing from the previous question. Ande, who has the genotype: AB*TUVFG RS*CDEWX is choose your answer... to have a phenotype as a result of their chromosome error. Ande and their partner (who does not have a chromosome error) produce a fertilized embryo. It is choose your answer... chromosome error due to the error in Ande's chromosomes. A that the embryo has a fatal choose your answer... likely (a calculable probability) unlikely (due to chance) --