Using the pedigree below for an autosomal dominant disorder to determine the phase (which ones are recombinants and which are non-recombinants? Identify them by pedigree position (11, 112, etc.) (SLO4) 11 III 2/2 2/2 1/2 1/1 2/2 2/2 2/2 2/2 1/2 2/2 1/2 2/2 1/2 2/2 Calculate the LOD score for each theta below for the pedigree above. Note: keep lots of places behind the decimal until the very end for accuracy. (SLO4)
Using the pedigree below for an autosomal dominant disorder to determine the phase (which ones are recombinants and which are non-recombinants? Identify them by pedigree position (11, 112, etc.) (SLO4) 11 III 2/2 2/2 1/2 1/1 2/2 2/2 2/2 2/2 1/2 2/2 1/2 2/2 1/2 2/2 Calculate the LOD score for each theta below for the pedigree above. Note: keep lots of places behind the decimal until the very end for accuracy. (SLO4)
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