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A: Answer is d.) Steroid hormone receptors.
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When activating what kind of receptor do you get the fastest (physiological) response? Select an option:
a.Transport protein-coupled receptors
b.G-protein-coupled receptorsIntracellular receptors
c.Ion channel coupled receptorsTyrosine kinase-coupled receptors
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- Which of the following receptor types is NOT a membrane receptor? a. Channel-linked receptor b. Enzymatic receptor c. G protein–coupled receptor d. Steroid hormone receptorsWhich of the following would inhibit the activity of TGF-Beta receptor? multiple answers A. Deletion of Extracellular domain B. Tyrosine Kinase Inhibitor C. Mutation that prevents homodimerization of Type II Receptor D. Mutation of phosphorylation site on Type I receptor E. Inhibition Type II receptor binding to Type I receptorDescribe how a very small quantity of receptor ligand is capable of eliciting a strong response in a target cell through amplification.
- Briefly explain the difference between a receptor antagonist and a receptor inverse agonist. Describe both the resulting receptor conformation as well as the signal transduction.Which of the following statements is NOT true of tyrosine kinase-linked receptors? Select one a Monomeric receptors are often induced to dimerize upon ligand binding b. The cytoplasmic side of the receptor contains a kinase enzyme domain that is activated upon ligand binding c. The activated receptors attract and activate G proteins to continue the signal pathwayxytocin stimulates contraction of smooth muscles in the breast and uterine wall. The key step in muscle contraction is release of calcium from internal cell stores. With which type of receptor does oxytocin interact to cause muscle contraction? A. Gαi-coupled receptor B. Tyrosine kinase coupled receptor C. Cytokine type 1 receptor D. Ser/Thr kinase receptor E. Gαq-coupled receptor
- Define the following terms: a. G protein-coupled receptor kinase b. β-arrestin c. enzyme-linked receptor d. guanylin e. RTKExplain whether the specificity of interaction will be high or low for each given situation. a. The value of KD of the ligand's interaction to the target receptor is very much lower than the value of KD of the ligand's interaction to off-targets. b. The ligand concentration [L] is higher than the KD value of its interaction with the target and the KD value of its interaction to off-targets.Explain whether the specificity of interaction will be high or low for each given situation. a. The concentration of the ligand's complex to the target receptor equates to the concentration of the ligand's complex to off-targets. b. The target receptor's total concentration is very much higher than the off-target's total concentration.
- You can choose one or more than one option The dissociation constant (Kd) of a receptor is: BIOCHEMISTRY basic the concentration of a ligand that produces 100% occupancy of the receptor the concentration of a ligand that produces 50% of the maximal effect. the measurement of specificity between ligand and its receptor. the measurement of speed by which a ligand will dissociate from its receptor. the measurement of affinity between a ligand and its receptor and the inverse of the association constant. During an experiment with Drosophila, it was discovered that all females had red eyes. unlike males. A conclusion based on this observation would be: MOLECULAR BIOLOGY basic The gene for eye color is located on the X chromosome. The females are homozygotes The gene for eye color is dominant. The eye color results from multigenic linkage. The eye color phenotype is sex-linked A secondary lysosome: CELL BIOLOGY advanced a lysosome that provides a backup to the primary…Briefly compare ion channel–linked receptors, G protein–linked receptors, enzyme-linked receptors, and intracellular receptors.What are the advantages of having an enzyme (like adenylyl cyclase) involved in the initial response to receptor activation by a first messenger?